Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Local Linear Estimation for Covariate-Dependent Coefficients Model in Disease Mapping. [PDF]
Jiang Y, Lin PS, Zhu J, Lin FC.
europepmc +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Mapping the literature about brain-computer interface in rehabilitation: a graph-theory-based PCA framework for semantic space analysis. [PDF]
Coraci D, Regazzo G, Masiero S.
europepmc +1 more source
Gene set mediation analysis in high-dimensional epigenetic studies. [PDF]
Gao Y +9 more
europepmc +1 more source
Anticholinergic Burden and Falls in Older Adults: The Role of Functional Status. [PDF]
Mutlay F, Das M.
europepmc +1 more source
Development of a Digital Twin Monitoring Framework for Blade Polishing Robot Process Based on Cloud-Edge-Device. [PDF]
Wang N +5 more
europepmc +1 more source
Purine Metabolism Profiling Reveals Distinct Associations of Uric Acid, Xanthine, and Hypoxanthine with Neurological Severity and Functional Outcome After Acute Ischemic Stroke. [PDF]
Roman-Filip I +6 more
europepmc +1 more source
Total energy expenditure assessed by doubly labeled water in patients with myotonic dystrophy type 1: Associations with body composition and functional status. [PDF]
Umemoto G +7 more
europepmc +1 more source

