Results 111 to 120 of about 6,284,740 (249)

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Oxytocin pathway gene variation and corticostriatal resting-state functional connectivity

Comprehensive Psychoneuroendocrinology
Genetic variations in single nucleotide polymorphisms (SNPs) within oxytocin pathway genes have been linked to social behavior and neurodevelopmental conditions. However, the neurobiological mechanisms underlying these associations remain elusive.
Shanshan Xiao, Håkan Fischer, Natalie C. Ebner, Gull Rukh, Junhua Dang, Lars Westberg, Helgi B. Schiöth   +6 more
doaj   +1 more source

Taxonomic, Genomic, and Functional Variation in the Gut Microbiomes of Wild Spotted Hyenas Across 2 Decades of Study. [PDF]

mSystems, 2023
Rojas CA, Holekamp KE, Viladomat Jasso M, Souza V, Eisen JA, Theis KR.   +5 more
europepmc   +1 more source

Genomic and Functional Variation at a Normal Human Centromere

, 2015
Centromeres are chromosomal loci essential for genome stability. Their malfunction can cause chromosome instability associated with cancer, infertility, and birth defects.
Aldrup-MacDonald, Megan Elizabeth
core  

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Study on the variation of functional traits and environmental driving factors of different species origins of Acer truncatum in the Horqin Sandy Land

Xibei zhiwu xuebao
[Objective] The study of the functional trait variation and environmental drivers of woody oilseed plants in different origins is of great significance for the construction of core breeding populations and the selection of improved seeds.
WANG Yuqing, WU Sha, XU Yan, XIN Xuebing, LI Xiaogang, PEI Shunxiang   +5 more
doaj   +1 more source

Selection shapes the landscape of functional variation in wild house mice. [PDF]

BMC Biol, 2021
Lawal RA, Arora UP, Dumont BL.
europepmc   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Genomic and Functional Variation of the Chlorophyll d-Producing Cyanobacterium Acaryochloris marina. [PDF]

Microorganisms, 2022
Miller SR, Abresch HE, Baroch JJ, Fishman Miller CK, Garber AI, Oman AR, Ulrich NJ.   +6 more
europepmc   +1 more source

Contrasting drivers of community-level trait variation for vascular plants, lichens and bryophytes across an elevational gradient [Elektronisk resurs]

, 2019
1. Across environmental gradients, community-level functional traits of plants can change due to species turnover, intraspecific variation and their covariation.
Wardle, David,, Sveriges lantbruksuniversitet.   +1 more
core   +1 more source