Results 61 to 70 of about 80,406 (296)

Ratio of Loss and Storage Moduli Determines Restitution Coefficient in Low-Velocity Viscoelastic Impacts [PDF]

, 2020
Impact tests are an important tool to analyze dynamic material properties of viscoelastic media in technology and biology. In this context, rigorous contact mechanical models of the collision problem are necessary to adequately interpret data from impact
Willert, Emanuel
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Group and Phase Velocity of Love Waves Propagating in Elastic Functionally Graded Materials

Archives of Acoustics, 2015
This paper presents a theoretical study of the propagation behaviour of surface Love waves in nonhomogeneous functionally graded elastic materials, which is a vital problem in acoustics.
Piotr KIEŁCZYŃSKI, Marek SZALEWSKI, Andrzej BALCERZAK, Krzysztof WIEJA   +3 more
doaj   +1 more source

A parametric study on the buckling of functionally graded material plates with internal discontinuities using the partition of unity method

, 2013
In this paper, the effect of local defects, viz., cracks and cutouts on the buckling behaviour of functionally graded material plates subjected to mechanical and thermal load is numerically studied.
Chakraborty, S, Ganapathi, M, Natarajan, S, Subramaniam, M   +3 more
core   +1 more source

A multi-material virtual prototyping system for biomedical applications [PDF]

, 2009
This paper describes a multi-material virtual prototyping (MMVP) system for modelling and digital fabrication of discrete and functionally graded multi-material objects for biomedical applications.
Cheung, HH, Choi, SH, Zhu, WK
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Bending and vibration of functionally graded material sandwich plates using an accurate theory

, 2012
In this paper, the bending and the free flexural vibration behaviour of sandwich functionally graded material (FGM) plates are investigated using QUAD-8 shear flexible element developed based on higher order structural theory.
Ali, Anderson, Bhangale, Das, Ferreira, Ganapathi, Ganapathi Manickam, Koizumi, Li, Makhecha, Murukami, Natarajan, Nosier, Pan, Reddy, Roderigues, S. Natarajan, Shen, Singh, Vel, Zenkour, Zenkour   +21 more
core   +1 more source

Graded ferroelectric capacitors with robust temperature characteristics [PDF]

, 2006
Ferroelectric thin films offer the possibility of engineering the dielectric response for tunable components in frequency-agile rf and microwave devices. However, this approach often leads to an undesired temperature sensitivity.
Bhattacharya, Kaushik, Dayal, Kaushik, El-Naggar, Mohamed Y., Goodwin, David G.   +3 more
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source