Results 71 to 80 of about 38,875 (281)

Analysis of non symmetric FG sandwich plates under Thermo-mechanical loading using a novel shear deformation theory with stretching effect

MATEC Web of Conferences, 2018
The analysis of non-symmetric functionally graded sandwich plates under thermo-mechanical loading is developed using a novel hyperbolic shear deformation theory and considering thickness stretching effects.
Saidi H., Bouchafa A., Tounsi A., Adda.Bedia A. E.A.   +3 more
doaj   +1 more source

A parametric study on the buckling of functionally graded material plates with internal discontinuities using the partition of unity method

, 2013
In this paper, the effect of local defects, viz., cracks and cutouts on the buckling behaviour of functionally graded material plates subjected to mechanical and thermal load is numerically studied.
Chakraborty, S, Ganapathi, M, Natarajan, S, Subramaniam, M   +3 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Numerical modelling of functionally graded coatings [PDF]

, 2013
Peer ...
Heidari, Maryam, Kashtalyan, Maria
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Vibration and Static Analysis of Functionally Graded Porous Plates [PDF]

Journal of Applied and Computational Mechanics, 2017
This research deals with free vibration and static bending of a simply supported functionally graded (FG) plate with the porosity effect. Material properties of the plate which are related to its change are position-dependent.
Şeref Doğuşcan Akbaş
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Nonlinear vibration of thick FGM plates on elastic foundation subjected to thermal and mechanical loads using the first-order shear deformation plate theory

Cogent Engineering, 2015
This paper presents an analytical approach to investigate the nonlinear dynamic response and vibration of thick functionally graded material (FGM) plates using both of the first-order shear deformation plate theory and stress function with full motion ...
Nguyen Dinh Duc, Pham Hong Cong
doaj   +1 more source

Isogeometric Analysis for Active Control of Piezoelectric Functionally Graded Plates in Thermal Environment

Shock and Vibration, 2021
An isogeometric analysis (IGA) method is proposed for investigating the active shape and vibration control of functionally graded plates (FGPs) with surface-bonded piezoelectric materials in a thermal environment.
Tao Liu, Yafen Jiang, Shujun Li, Qingyun Liu, Chao Wang   +4 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source