Results 81 to 90 of about 38,875 (281)

Thermoelastic stability of thick imperfect functionally graded plates

Vietnam Journal of Mechanics, 2010
This paper investigates buckling of thick functionally graded plates with initial geometrical imperfection under thermal loadings. The equilibrium, stability, and compatibility equations of an imperfect functionally graded plate are derived using the ...
Hoang Van Tung, Nguyen Dinh Duc
doaj   +1 more source

Free Vibration Analysis of 2D Functionally Graded Annular Plate considering the Effect of Material Composition via 2D Differential Quadrature Method [PDF]

Mechanics of Advanced Composite Structures, 2015
This study investigates the free vibration of the Two-Dimensional Functionally Graded Annular Plates (2D-FGAP). The theoretical formulations are based on the three-dimensional elasticity theory with small strain assumption.
Mohammad Nejati, Hamid Mohsenimonfared, Ali Asanjarani   +2 more
doaj   +1 more source

Refined shell elements for the analysis of functionally graded structures [PDF]

, 2011
The present paper considers the static analysis of plates and shells made of Functionally Graded Material (FGM), subjected to mechanical loads. Refined models based on the Carrera's Unified Formulation (CUF) are employed to account for grading ...
Carrera, Erasmo, Chinosi, C., Cinefra, Maria, Della Croce, L.   +3 more
core   +1 more source

Thermal buckling of imperfect functionally graded plates

International Journal of Solids and Structures, 2006
AbstractThermal buckling analysis of rectangular functionally graded plates (FGPs) with geometrical imperfections is presented in this paper. The equilibrium, stability, and compatibility equations of an imperfect functionally graded plate are derived using the classical plate theory.
Samsam Shariat, B.A., Eslami, M.R.
openaire   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Application of the R-Functions Theory to Problems of Nonlinear Dynamics of Laminated Composite Shallow Shells and Plates: Review [PDF]

, 2016
A review of studies performed using the R-functions theory to solve problems of nonlinear dynamics of plates and shallow shells is presented. The systematization of results and studies for the problems of free and parametric vibrations and for problems
Kurpa, Lidiya
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Study on the nonlinear vibration of tri-directional functionally graded sandwich plates partially supported by Pasternak foundation subjected to blast loading

Defence Technology
This paper aims to explore and quantify the nonlinear vibration response of tri-directional functionally graded sandwich (3D-FGSW) plates partially supported by a Pasternak foundation (PF) subjected to blast loading (BL).
Trung Thanh Tran, Huyen Thi Huong Truong, Pham Binh Le   +2 more
doaj   +1 more source

Static and vibration analysis of functionally graded beams using refined shear deformation theory [PDF]

, 2013
Static and vibration analysis of functionally graded beams using refined shear deformation theory is presented. The developed theory, which does not require shear correction factor, accounts for shear deformation effect and coupling coming from the ...
A Chakraborty, A Nateghi, AE Alshorbagy, BV Sankar, Fawad Inam, G Giunta, G Giunta, H Zhu, H-T Thai, HK Ching, Huu-Tai Thai, JN Reddy, JN Reddy, M Aydogdu, M Benatta, M Birsan, M Salamat-talab, M Simsek, M Simsek, M Simsek, M Simsek, R Kadoli, S Ben-Oumrane, S Kapuria, SA Sina, SMR Khalili, Thuc P. Vo, Trung-Kien Nguyen, X-F Li, X-F Li, Z Zhong   +30 more
core   +2 more sources