Results 51 to 60 of about 66,953 (300)

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack   +39 more
wiley   +1 more source

Exact solution for bending analysis of functionally graded micro-plates based on strain gradient theory

open access: yesScience and Engineering of Composite Materials, 2018
In the present article, static analysis of thin functionally graded micro-plates, based on Kirchhoff plate theory, is investigated. Utilizing the strain gradient theory and principle of minimum total potential energy, governing equations of rectangular ...
Mohammadi Meisam   +3 more
doaj   +1 more source

Investigation of functionally graded TPMS structures fabricated by additive manufacturing

open access: yesMaterials & Design, 2019
Triply periodic minimal surfaces (TPMS), which have zero mean curvature and large surface areas, are discussed in this paper. Two TPMS structures, the Schwarz Primitive (P) and Gyroid, were designed with both uniform and graded density and fabricated ...
Shixiang Yu, Jinxing Sun, Jiaming Bai
doaj   +1 more source

Receding Contact Problem of Multi-Layered Elastic Structures Involving Functionally Graded Materials

open access: yesCrystals, 2022
This paper studies a receding contact problem of a functionally graded layer laminate pressed against a functionally graded coated homogeneous half-plane substrate by a rigid flat indenter.
Jie Yan, Cong Wang
doaj   +1 more source

A parametric study on the buckling of functionally graded material plates with internal discontinuities using the partition of unity method

open access: yes, 2013
In this paper, the effect of local defects, viz., cracks and cutouts on the buckling behaviour of functionally graded material plates subjected to mechanical and thermal load is numerically studied.
Chakraborty, S   +3 more
core   +1 more source

A quasi-3D hyperbolic shear deformation theory for functionally graded plates [PDF]

open access: yes, 2013
A quasi-3D hyperbolic shear deformation theory for functionally graded plates is developed. The theory accounts for both shear deformation and thickness-stretching effects by a hyperbolic variation of all displacements across the thickness, and satisfies
Bui, Tinh   +3 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Design of Titanium Alloy Femoral Stem Cellular Structure for Stress Shielding and Stem Stability: Computational Analysis

open access: yesApplied Sciences, 2022
The main objective of this study is to design titanium alloy femoral stems with cubic porous structures that will be able to reduce stress shielding and promote stem stability.
Naser Fawzi Al Zoubi   +3 more
doaj   +1 more source

Materials Design - Towards a Functionally Graded Electrical Conductor [PDF]

open access: yes, 2004
In this study, we discuss functionally graded (FG) materials as pulsed electrical conductors. These conductors can be designed to be more efficient and longer lasting by applying numerical modeling tools.
Hsieh, K., Persad, C., Satapathy, S.
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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