Results 61 to 70 of about 67,654 (301)
Applied Sciences, 2022 The main objective of this study is to design titanium alloy femoral stems with cubic porous structures that will be able to reduce stress shielding and promote stem stability.
Naser Fawzi Al Zoubi +3 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Materials & Design, 2021 This paper aims to evaluate the potential use of an innovative functionally graded lattice-filled composite beam composed of axial and radial graded three-dimensional lattice cores.
Yuze Nian +5 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
A nonlocal sinusoidal plate model for micro/nanoscale plates [PDF]
, 2014 A nonlocal sinusoidal plate model for micro/nanoscale plates is developed based on Eringen’s nonlocal elasticity theory and sinusoidal shear deformation plate theory.
Lee, Jaehong +3 more
core +1 more source
FUNCTIONALLY GRADED COMPOSITES FOR AXISYMMETRIC MORPHING STRUCTURES
, 2023 An inverse design framework is proposed to form morphing structures using functionally graded composites with varying modulus profile.
Hirak Kansara +3 more
openaire +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Dynamic performance of functionally graded composite structures with viscoelastic polymers
Scientific ReportsThe functionally graded composite structures with viscoelastic polymers inherits the excellent performance of functionally graded composites and also possesses large damping performance, which has broad application prospects in the aerospace and ...
Shaoqing Wang +4 more
doaj +1 more source
A new sinusoidal shear deformation theory for bending, buckling, and vibration of functionally graded plates [PDF]
, 2012 A new sinusoidal shear deformation theory is developed for bending, buckling, and vibration of functionally graded plates. The theory accounts for sinusoidal distribution of transverse shear stress, and satisfies the free transverse shear stress ...
Ameur +38 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source