Results 51 to 60 of about 67,654 (301)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Exact solution for bending analysis of functionally graded micro-plates based on strain gradient theory

open access: yesScience and Engineering of Composite Materials, 2018
In the present article, static analysis of thin functionally graded micro-plates, based on Kirchhoff plate theory, is investigated. Utilizing the strain gradient theory and principle of minimum total potential energy, governing equations of rectangular ...
Mohammadi Meisam   +3 more
doaj   +1 more source

A parametric study on the buckling of functionally graded material plates with internal discontinuities using the partition of unity method

open access: yes, 2013
In this paper, the effect of local defects, viz., cracks and cutouts on the buckling behaviour of functionally graded material plates subjected to mechanical and thermal load is numerically studied.
Chakraborty, S   +3 more
core   +1 more source

3D hybrid wound devices for spatiotemporally controlled release kinetics [PDF]

open access: yes, 2012
This paper presents localized and temporal control of releasekinetics over 3-dimensional (3D) hybridwounddevices to improve wound-healing process. Imaging study is performed to extract wound bed geometry in 3D.
Koc, Bahattin   +3 more
core   +1 more source

Functionally graded engineering structures: An overview

open access: yesEngineering Structures
Functionally graded materials (FGMs) are engineered composites inspired by natural materials, which have been extensively investigated over the last decade as a design concept for improving the mechanical and multifunctional performances of engineering structures.
Liangteng Guo   +4 more
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Analysis of sandwich beam structures using kriging based higher order models [PDF]

open access: yes, 2015
Functionally graded composite materials can provide continuously varying properties, which distribution can vary according to a specific location within the composite.
Barbosa, Joaquim   +2 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Pore functionally graded Ti6Al4V scaffolds for bone tissue engineering application

open access: yesMaterials & Design, 2019
A significant requirement for a bone implant is to let bone cells grow better. However, how to increase the cellular activity of the scaffold at a certain elastic modulus remains unclear.
Su Wang   +5 more
doaj   +1 more source

A COMBINED STRAIN ELEMENT TO FUNCTIONALLY GRADED STRUCTURES IN THERMAL ENVIRONMENT

open access: yesActa Polytechnica, 2020
Functionally graded materials are commonly used in a thermal environment to change the properties of constituent materials. They inherently withstand high temperature gradients due to a low thermal conductivity, core ductility, low thermal expansion ...
Hoang Lan Ton-That
doaj   +1 more source

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