Results 141 to 150 of about 1,556,466 (314)
Despite the well-documented success of cognitive restructuring techniques in the treatment of anxiety disorders, there is still little clarity on which cognitions underpin fear and anxiety in children with high-functioning spectrum disorders (HFASD ...
Simon C Hunter +7 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
PurposeA total knee arthroplasty (TKA) is a cost-effective option to relieve pain and improve knee function in patients suffering from osteoarthritis. However, results differ among patients.
Berghmans, Danielle D. P. +4 more
core +1 more source
Function beyond function? Reflections on the functionality of the autonomous
Of all the arts, music has always seemed to be the most autonomous, free from the bonds and limits of representation. Hence its functionality within this very autonomy or non-functionality: its link with the sacred, elevation over the economics of survival, its ritual value.
openaire +2 more sources
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Territorial Functioning, Victimisation And Fear Of Crime: A Comparative Study Of High And Low Crime Rate Estates. [PDF]
There is substantial empirical support that links territorial functioning with low crime and fear of crime in the residential setting. However, for the concept to be useful in preventing crime and fear of crime, it is important for it to operate in ...
Ahmad, A.G. +3 more
core
Spatial Function-on-Function Regression
43 pages, 6 figures, 3 ...
Ufuk Beyaztas +5 more
openaire +2 more sources
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
The associations between socio-economic position (SEP) and physical functioning have frequently been investigated but little is known about which measures of SEP are the best to use for older people.
Gjonca, E. +4 more
core

