Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas +39 more
wiley +1 more source
Structural Insights into the HWE Histidine Kinase Family: The Brucella Blue Light-Activated Histidine Kinase Domain [PDF]
, 2016 In response to light, as part of a two-component system, the Brucella blue light-activated histidine kinase (LOV-HK) increases its autophosphorylation, modulating the virulence of this microorganism.
Arrar, Mehrnoosh +9 more
core +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
A genetic toolkit for the analysis of metabolic changes in Drosophila provides new insights into metabolic responses to stress and malignant transformation [PDF]
, 2019 Regulation of the energetic metabolism occurs fundamentally at the cellular level, so analytical strategies must aim to attain single cell resolution to fully embrace its inherent complexity.
Behrensen, C. +3 more
core +1 more source
3D‐Printed Giant Magnetoresistive (GMR) Sensors Based on Self Compliant Springs
Advanced Engineering Materials, EarlyView.This work explores 3D‐printed GMR sensors utilizing self‐compliant spring structures and conductive PLA composites. By optimizing arm width, we achieved high piezoresistive (0.34%/mm) and magnetoresistive (0.77%/mT) sensitivities. Demonstrated through Bluetooth‐integrated pressure and magnetic position sensing, these full printed low‐cost, customizable
Josu Fernández Maestu +4 more
wiley +1 more source
Xanthan pyruvilation is essential for the virulence of Xanthomonas campestris pv. campestris [PDF]
, 2016 Xanthan, the main exopolysaccharide (EPS) synthesized by Xanthomonas spp., contributes to bacterial stress tolerance and enhances attachment to plant surfaces by helping in biofilm formation.
Bianco, María Isabel +8 more
core +1 more source
Advanced Functional Materials, EarlyView.MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández +7 more
wiley +1 more source
Community Foundations: Learning from a Collective Experience: Process of Systematization [PDF]
, 2004 The report of a community foundation strengthening program involving eight Mexican community foundations: Tecate CF, Frontera Norte CF, Matamoros CF, Oaxaca CF, Puebla CF, Fundación Comunidad, Fundación del Empresariado Chihuahuense (FECHAC), and ...
Elena Luengas +3 more
core
Sex differences in the pituitary TGFβ1 system: the role of TGFβ1 in prolactinoma development [PDF]
, 2019 Prolactinomas are the most frequent functioning pituitary adenomas, and sex differences in tumor size, behavior and incidence have been described. These differences have been associated with earlier diagnosis in woman, as well as with serum estradiol ...
Abeledo Machado, Alejandra Inés +6 more
core +1 more source
Shape‐Changing Multiphase Microparticles from Complex Liquid Crystal Emulsions
Advanced Functional Materials, EarlyView.Liquid crystalline network (LCN) microparticles are prepared from single, double (Janus), and triple emulsions through a simple and scalable bulk‐emulsification strategy. Under heating, the particles exhibit robust, reversible, large‐amplitude deformations that depend both on the morphology and the liquid crystals director field configuration.
Marco Turriani +3 more
wiley +1 more source