Results 41 to 50 of about 500,560 (272)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

TURISMO DE HACIENDA, TRABAJO FEMENINO Y TRANSFORMACIONES LOCALES. EL CASO DE LOS TALLERES ARTESANALES DE LA FUNDACIÓN HACIENDAS DEL MUNDO MAYA

open access: yes, 2014
Hacienda tourism is a form of cultural tourism mainly promoted by business groups. One of these groups upon which this article is focused, the Fundacion Haciendas del Mundo Maya is responsible for a community development program. As part of their project,
I. Reyes   +2 more
semanticscholar   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Über einen die Erzeugung und Verwandlung des Lichtes betreffenden heuristischen Gesichtspunkt [AdP 17, 132 (1905)]

open access: yesAnnals of Physics, 2005
Este material fue digitalizado en el marco del Proyecto subvencionado por la Fundacion Antorchas y se encuentra en la Biblioteca del Departamento de Fisica de la Facultad de Ciencias Exactas de la Universidad Nacional de La Plata.
A. Einstein
semanticscholar   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Photoimagen. Un evento y ahora un centro de la imagen.

open access: yesPeriférica, 2011
La fundación Imagen 83 creada por Mayra Johnson celebra el festival de fotografía Photoimagen y nos cuenta la experiencia de exposiciones y eventos paralelos al mismo.
Fundación Imagen 83 Fundación Imagen 83
doaj  

Museo Teatro Romano de Cartagena [PDF]

open access: yesBoletín del Museo Arqueológico Nacional, 2017
El proyecto de recuperación del teatro romano de Cartagena ha contemplado la integración de los restos en el tejido urbano así como su adecuada conservación y exposición con fines didácticos y culturales.
Elena Ruiz Valderas
doaj  

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Transición a la democracia, militancia y proyecto étnico : la fundación de la organización mapuche Consejo de Todas las Tierras, 1978-1990

open access: yesEstudios Sociológicos de El Colegio de México, 2009
En el articulo se analiza la fundacion de la organizacion mapuche Consejo de Todas las Tierras, en el marco de la transicion chilena a la democracia y de las tensiones que se producen entre el liderazgo etnico y la estructura de participacion dada por ...
Christian Martínez Neira
semanticscholar   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub   +24 more
wiley   +1 more source

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