Results 51 to 60 of about 17,091 (293)

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

open access: yesArthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie   +3 more
wiley   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh   +5 more
wiley   +1 more source

The Nuremberg Trials and The Principle of Respect for The Practice of the European Court of Human Rights

open access: yesRUDN Journal of Law, 2016
In 1946, the Nuremberg trials established the legal end of the Second World War. Gross and massive violations of human rights in Europe were a powerful incentive to the establishment of effective guarantees for fundamental human rights at the regional ...
Andrei M Nikolaev
doaj  

High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello   +5 more
wiley   +1 more source

THE INTERNET BETWEEN PROMOTION AND INFRINGEMENT OF THE FUNDAMENTAL RIGHTS FREEDOMS vs. CYBERCRIMES [PDF]

open access: yes
The Internet has become a mean by which individuals can exercise their right to freedom of opinion and expression, as well as the freedom of association, which, both play a crucial role in supporting democracy and guaranteeing human rights.
Silvia-Maria Tăbușcă (Martiș)
core  

Constitutional Court activism and European legal standards

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2014
Human and minority rights and freedoms flourished and achieved overall affirmation at the end of the twentieth and the beginning of the twenty-first century everywhere in the world, particularly in Europe.
Mato Arlović
doaj  

Los conflictos entre libertades económicas yderechos fundamentales en la jurisprudencia del Tribunal de Justicia de laUnión Europea

open access: yesRevista de Derecho Político, 2011
Como es sabido, la protección de los derechos fundamentales ha cambiado mucho en la Unión Europea. En un primer momento, los Tratados constitutivos de las Comunidades Europeas guardaban silencio sobre la protección de los derechos humanos, y fue el ...
Joaquín Sarrión Esteve
doaj   +1 more source

Cumulative Social Disadvantage and Disease Activity in Juvenile Idiopathic Arthritis: A Childhood Arthritis and Rheumatology Research Alliance Registry Study

open access: yesArthritis Care &Research, EarlyView.
Objective Social determinants of health (SDOH) contribute to juvenile idiopathic arthritis (JIA) disparities, but most studies have assessed SDOH independently rather than cumulatively across individual, family, and neighborhood levels. Using a socioecological framework, we investigated the relationship among cumulative social disadvantage ...
William Daniel Soulsby   +448 more
wiley   +1 more source

The Observance of Human Rights and Freedoms in the Extradition Proceedings at National and International Levels

open access: yesJournal of Danubian Studies and Research, 2013
The fundamental rights and freedoms contained in international documents may be the object of the denial of an extradition request as independent exceptions, even if they are not covered by extradition treaties.
Mariana (Mitra) Radu, Catalina Mititelu
doaj  

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