Results 161 to 170 of about 4,480,200 (305)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Reply to Knobloch [PDF]

, 2017
Fundamental mathematics, Blasjo, V.N.E., Sub Fundamental Mathematics   +2 more
core   +1 more source

Evidence for Quark Confinement in the Proton. [PDF]

Research (Wash D C)
Ji X, Miller GA, Yang C.
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

A strong and ductile Super Kovar alloy via fully coherent nanoprecipitates. [PDF]

Sci Adv
Yu C, Chen Y, Zhu H, Yang Y, Zhang Y, Gu L, Khmelevskyi S, Kato K, An K, Yu D, Chen Y, Ma X, Yang W, Raabe D, Xing X.   +14 more
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Microwave diffractive neural network chips for sensing and computing. [PDF]

Sci Adv
Chen L, Wu QW, Gu Z, Ma Q, Xiao L, Tian Z, Su WQ, Cui HY, You JW, Cui TJ.   +9 more
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Editorial: Organoids and 3D culture: bridging tissue complexity in biomedical research. [PDF]

Front Med (Lausanne)
Vezzani B, Genovese I.
europepmc   +1 more source

Fundamentals of Matrix Computations.

Mathematics of Computation, 1992
G. W. S., David S. Watkins
openaire   +2 more sources