Results 61 to 70 of about 31,277 (241)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
BACKGROUND: In typically developing children, physical fitness and fundamental motor skills are closely related and develop in tandem. Whether the strength of this relationship differs in children with generalized joint hypermobility remains unclear ...
Kshama Shetty +5 more
doaj +1 more source
Fundamental motor skill proficiency is necessary for children's motor activity inclusion [PDF]
Motor development is influenced by many factors such as practice and appropriate instruction, provided by teachers, even in preschool and elementary school. The goal of this paper was to discuss the misconception that maturation underlies children's motor skill development and to show that physical education, even in early years of our school system ...
openaire +7 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Background and Objective: This study aimed to examine the relationship between age, gender and body mass index with performance of fundamental motor skills among children aged 7-10 years.
Amir Shams, Roshanak Vameghi
doaj
A Factorial Analysis of Ability in Fundamental Motor Skills
Mode of access: Internet.
openaire +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Fundamental motor skills (FMS) are the basic elements of more complex sport-specific skills and should be mastered at the end of early childhood; however, the relationship between FMS and sport-specific skills has not yet been verified in prepubertal ...
Jakub Kokstejn +4 more
doaj +1 more source
Proposal for a new method for teaching fundamental motor skills
AbstractDuring the period of acquisition and first practice of movement skills, learning becomes more effective when various sensory channels are used. According to the Dual Coding Theory, students as learners code both visually and verbally incoming information into knowledge that can be stored and retrieved for subsequent use.
Dania, A., Tyrovola, V., Koutsouba, M.
openaire +2 more sources
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

