Results 71 to 80 of about 173,796,379 (301)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Accurate fundamental parameters of CoRoT asteroseismic targets

open access: yes, 2009
Context. The CoRoT satellite has provided high-quality light curves of several solar-like stars. Analysis of these light curves provides oscillation frequencies that make it possible to probe the interior of the stars.
H. Bruntt, Bruntt, H.
core   +1 more source

Time-series Spectroscopy and TESS Photometry of the Oscillating Eclipsing Algol System V389 Cassiopeiae

open access: yesThe Astronomical Journal
We present the results from a detailed analysis of our time-series spectroscopic observations and the Transiting Exoplanet Survey Satellite (TESS) photometric data of the eclipsing binary V389 Cas.
Pakakaew Rittipruk   +6 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Detection of the Temperature Dependence of the White Dwarf Mass–Radius Relation with Gravitational Redshifts

open access: yesThe Astrophysical Journal
Models predict that the well-studied mass–radius relation of white dwarf stars depends on the temperature of the star, with hotter white dwarfs having larger masses at a given radius than cooler stars.
Nicole R. Crumpler   +10 more
doaj   +1 more source

Comparative Study of TESS Photometry and Radial Velocities on Six Early K-type Contact Binaries with Similar Periods around 0.268 Day

open access: yesThe Astronomical Journal, 2023
High-precision light curves were extracted from TESScut images. Together with APOGEE and LAMOST medium-resolution spectra, a joint study was made for six early K-type contact binary candidates selected unbiasedly with orbital periods around 0.268 day. It
N.-P. Liu   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

TESS Asteroseismic Masses and Radii of Red Giants with (and without) Planets

open access: yesThe Astrophysical Journal
We present a study of asteroseismically derived surface gravities, masses, and radii of a sample of red giant stars both with and without confirmed planetary companions using TESS photometric light curves. These red giants were drawn from radial velocity
Myles Pope   +3 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Fundamental parameters of He-weak and He-strong stars [PDF]

open access: yes, 2019
Context. He-weak and He-strong stars are chemically peculiar AB objects whose He lines are anomalously weak or strong for their MK spectral type. The determination of fundamental parameters for these stars is often more complex than for normal stars due ...
Arias, María Laura   +5 more
core  

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