Results 91 to 100 of about 129,190 (318)

The Disposal of COVID-19 Dead Bodies: Impact of Sri Lanka's Response on Fundamental Rights. [PDF]

J Hum Rights Pract, 2021
Marsoof A.
europepmc   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Fundamental rights and private law:<br> A relationship of subordination or complementarity?

Utrecht Law Review, 2007
Originally, private law was considered to be immune from the effect of fundamental rights, the function of which was limited to being individual defences against the vigilant eye of the state.
Olha O. Cherednychenko
doaj   +1 more source

The need for global safeguards for fundamental rights of children at risk of infant oral mutilation (IOM). [PDF]

BMJ Glob Health, 2022
Kemoli AM, Sidhu SK, Cheng L.
europepmc   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Fundamental Rights in Austrian Civil Law

Časopis pro Právní Vědu a Praxi, 2010
It could be shown that fundamental rights play a vital role in private law. Generally, they are not applied directly, but they have to be taken into account when it comes to the interpretation of provisions governing the private law relations between two
Martin Schauer
doaj  

Democratic citizenship vs. national identity: the political rights of foreigners in Spain / Ciudadanía democrática vs. identidad nacional: los derechos políticos de los extranjeros en España

Barataria, 2015
The relationship between sovereignty-people-nationality-citizenship should be revised. Democratic citizenship, only valid in the 21st century concept implies that all people, regardless of their origin, could have direct involvement in the affairs of ...
Antonia Durán Ayago
doaj   +1 more source

Towards the engagement of citizens in SOSTs decision-making: participatory models setting a common ground for border surveillance and respect of fundamental rights. Findings from ARESIBO H2020 project. [PDF]

Open Res Eur, 2023
Laterza R, Del Bianco D, Velea R, Ferrari O, De Sabbata L, Benedetti E.   +5 more
europepmc   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source