Results 91 to 100 of about 5,275,514 (388)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Collision and competition of fundamental rights in German law [PDF]
Pravni Zapisi, 2018 Along with vertical effect of fundamental rights, which is undisputable, a more detailed analysis of the bonding-clause from Article 1, Paragraph 3 of the Basic Law for the Federal Republic of Germany has shown that fundamental rights can also develop a ...
Damnjanović Vojislav
doaj
Balancing Fundamental Rights with Economic Freedoms According to the European Court of Justice
Utrecht Law Review, 2013 The development of fundamental rights within the EU legal order has come to a climax through the entry into force of the Treaty of Lisbon in December 2009.
Sybe A. de Vries
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
A European Agency for Artificial Intelligence: Protecting fundamental rights and ethical values
Computer Law and Security Review, 2022 B. Stahl +3 more
semanticscholar +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Homoafetive Union: A Question of Fundamental Rights
Revista Brasileira de Direitos e Garantias Fundamentais, 2016 It analyzes the right to same-sex marriage. It presents different views on subjects related to the subject, to identity and to gender. It addresses fundamental rights and the constitutional principles applicable to the topic.
Renata Caroline Pereira Reis Mendes +1 more
doaj +1 more source
New digital rights: Imagining additional fundamental rights for the digital era
Computer Law and Security Review, 2022 B. Custers
semanticscholar +1 more source
Critical analysis of law, 2017 Mireille Hildebrandt’s Smart Technologies and the End(s) of Law (2015) raises questions for law that are best characterized as meta-institutional. This review essay considers the implications of Hildebrandt’s work for the conceptualization of fundamental
Julie E. Cohen
semanticscholar +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source