Results 51 to 60 of about 4,837,102 (259)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Franet National contribution to the Fundamental Rights Report 2021: Portugal

open access: yes, 2021
Disclaimer: This document was commissioned under contract by the European Union Agency for Fundamental Rights (FRA) as background material for the project ‘FRA Fundamental Rights Report 2021”.
Henriques, Marina   +7 more
core  

Quel acces au juge pour protéger les droits fondamentaux dans l’Union européenne? [PDF]

open access: yesRomanian Journal of European Affairs, 2005
This article has as ambition to open the debate regarding the new role of human rights promoter assumed by the European Union within the context of adoption of the Charter of fundamental rights. The object of this article is to analyze the efficiency and
Ioana Răducu
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

National Action Plan on Fundamental and Human Rights 2017–2019

open access: yes, 2017
In the Government's Human Rights Report submitted to Parliament in 2014, the Government pledged to prepare a national action plan on promoting fundamental and human rights in Finland at the beginning of the following government term.

core   +1 more source

New numbers and what they tell us about child workers in the world today

open access: yesSafety and Health at Work, 2022
Michaelle De Cock, Federico Blanco
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Legal environment and space of civil society organisations in supporting fundamental rights and the rule of law [PDF]

open access: yes, 2022
DISCLAIMER: This document was commissioned under contract as background material for comparative analysis by the European Union Agency for Fundamental Rights (FRA) for the project ‘Fundamental Rights Platform and cooperation with civil society’.
Dias, João Paulo
core  

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