Results 111 to 120 of about 1,285,994 (279)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Evaluating Modular House Construction Projects: A Delphi Method Enhanced by Conversational AI

open access: yesBuildings
This study focuses on evaluating modular house construction projects, which is a critical segment within sustainable building practices. Despite the significant advantages of modular construction, such as enhanced resource efficiency and reduced ...
Augustinas Maceika   +2 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Spectrums of Solvable Pantograph Differential-Operators for First Order

open access: yesAbstract and Applied Analysis, 2014
By using the methods of operator theory, all solvable extensions of minimal operator generated by first order pantograph-type delay differential-operator expression in the Hilbert space of vector-functions on finite interval have been considered.
Z. I. Ismailov, P. Ipek
doaj   +1 more source

Examining the advocacy coalition framework for insight into shale gas development in US and UK political systems [PDF]

open access: yes, 2014
Master's Project (M.S.) University of Alaska Fairbanks, 2014The project considers the Advocacy Coalition Framework from the discipline of policymaking which is used to examine contentious and politically complex policy issues, particularly in energy and ...
Wolfley, Kathryn
core  

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Calculations of effective material tensors andthe electromechanical coupling coefficient of a type 1-3 composite transducer

open access: yesArchives of Acoustics, 2014
In this paper the purpose and manner of conducting the process of asymptotic homogenization of a type 1-3 composite structure are presented. The formulation of the homogenization process is reduced to numerical static analysis of an elementary symmetry ...
K. KYCIA, A. NOWICKI, O. GAJL, T.D. HIEN
doaj  

Catalan university libraries [PDF]

open access: yes, 1993
A university library is a cornerstone in the research of any country, and as the English say, it is the heart and measure of a university.Before we embark upon the study of Catalan university libraries it would be convenient to have an overview of the ...
Dilmé, M. Dolors   +1 more
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Generation and detection of incoherent hypersonic vibrations using superconducting tunnel junctions

open access: yesArchives of Acoustics, 2016
The investigations of superconducting tunnel junctions as phonon generators and detectors are reported. Theoretical predictions and the published results of the experimental research on such devices are briefly reviewed.
Mikołaj ALEKSIEJUK   +2 more
doaj  

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