Results 81 to 90 of about 10,132 (240)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Fundamentals of Engineering Graphics. Technical Drawing
Leidinyje pateikiama projekcinės braižybos teorija, praktinio darbo užduotys bei jų pavyzdžiai, taip pat supažindinama su techninių brėžinių atlikimo ir apipavidalinimo naujausiais Lietuvoje taikomais reikalavimais.
Vdovinskienė, Sonata, S. Vdovinskienė
core +1 more source
Advanced Computing Technology and Standardization Research
Advanced computing has become one of the most important technical fields in the 21st century. In the Internet of Things, artificial intelligence, autonomous driving, weather forecasting, aerospace, information research, life sciences, materials ...
Mengliang Li +3 more
core +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Les sciences de l'eau : présent et futur [PDF]
Les sciences de l'eau connaissent actuellement un développement accéléré. Plusieurs facteurs contribuent à cet élargissement de la base de connaissances explicatives et instrumentales sur l'eau. On note, par exemple,1.
de Marsily, G., Sasseville, J. L.
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
The current situation in the synthesis of complex organizational and technical systems in transport is characterized by a significant lag in the level of development of special mathematical and software, which significantly reduces the pace of ...
Igor Kartsan +4 more
core +1 more source

