Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Assessing tourism as a catalyst for rural development and community awareness: A case study of Coffee Bay, Mqanduli in the Eastern Cape Province. [PDF]
African Journal of Hospitality, Tourism and Leisure, 2019 The aim of this paper is to assess tourism as a catalyst for rural development and community awareness in a case study of Coffee Bay. Tourism is considered as a viable tool for economic development, specifically in the developing world.
Prof Dinesh Vallabh, Sakhumzi Woyikani
doaj
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Federal funding for the study of antimicrobial resistance in nosocomial pathogens: no ESKAPE.
Journal of Infectious Diseases, 2008 L. Rice
semanticscholar +1 more source
The Misallocation of Climate Research Funding
, 2020 Indra Overland, B. Sovacool
semanticscholar +1 more source
Effect of Entrepreneurial Skills Management and Funding on Small and Medium Enterprisesâ Performances at the Local Government Level in Northern Nigeria [PDF]
, 2015 Bello Sani Sambo +2 more
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Market Liquidity and Funding Liquidity
, 2005 L. Pedersen, Markus K. Brunnermeier
semanticscholar +1 more source
Giving New Zealand: Philanthropic Funding 2006 [PDF]
, 2007 This report provides measurement of New Zealanders' philanthropic funding for the 2005/2006 year and what these funds ...
Andrew Slack, Jason Leung-Wai
core