Results 31 to 40 of about 171,170 (252)

Inhibition of Obtusifolin on retinal pigment epithelial cell growth under hypoxia [PDF]

International Journal of Ophthalmology, 2019
AIM: To explore the effect of Obtusifolin on retinal pigment epithelial cell growth under hypoxia. METHODS: In vitro chemical hypoxia model of ARPE-19 cells was established using cobalt chloride (CoCl2). Cell viability was tested by cell counting kit-8 (
Li-Fei Wang, Zhong-Yang Yan, Ya-Lin Li, Yan-Hui Wang, Sheng-Juan Zhang, Xin Jia, Lu Lu, Yan-Xia Shang, Xin Wang, Yun-Huan Li, Shan-Yu Li   +10 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Quantificare il lusso attraverso i disiecta membra. La villa romana di Aiano (San Gimignano, Siena, Italia): l’ombra di un sogno.

Fundus
La villa di Aiano, tra il IV e la metà del V sec. d.C., conserva monumentali e sofisticate formule architettonico-planimetriche, le sole evidenze archeologiche non residuali di una fase residenziale di prestigio, completamente metabolizzata nell’alto ...
Marco Cavalieri
doaj   +1 more source

Towards Complete Ocular Disease Diagnosis in Color Fundus Image [PDF]

, 2022
Non-invasive assessment of retinal fundus image is well suited for early detection of ocular disease and is facilitated more by advancements in computed vision and machine learning.
Khanal, Aashis
core   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

La economía productiva del suburbio de Gerunda a través de las herramientas de hierro: un catálogo de la villa romana de Pla de l’Horta

Fundus
La villa romana de Pla de l’Horta, ubicada en el suburbium de Gerunda (Girona), constituye un ejemplo relevante de asentamiento productivo rural de época romana.
Ana Costa Solé, David Vivó Codina
doaj   +1 more source

Chronological Registration of OCT and Autofluorescence Findings in CSCR: Two Distinct Patterns in Disease Course

Diagnostics, 2022
Optical coherence tomography (OCT) and fundus autofluorescence (FAF) are important imaging modalities for the assessment and prognosis of central serous chorioretinopathy (CSCR).
Monty Santarossa, Ayse Tatli, Claus von der Burchard, Julia Andresen, Johann Roider, Heinz Handels, Reinhard Koch   +6 more
doaj   +1 more source

Large‐scale Whole‐Exome Sequencing Defines the Protein‐Coding Architecture of Retinal Structure, Visual Function, and Major Blinding Diseases

Advanced Science, EarlyView.
Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li, Yijun Ge, Jingxiao Du, Liu Yang, Bangsheng Wu, Chenyue Hang, Mengxi Shen, Yimin Mao, Ting Zhang, Qiyu Bo, Tianyuan Zhao, Yutian Jiao, Yazhi Wang, Shunxiang Gao, Jieqiong Chen, Junran Sun, Tong Li, Huixun Jia, Yang Dou, Wei Cheng, Xiaoling Wan, Jintai Yu, Xiaodong Sun, Bai Lu   +23 more
wiley   +1 more source

L’anomenada «crisi del segle III» en el quadrant nord-oriental del conuentus Tarraconensis

Fundus
Observar, en un territori reduït i prou ben conegut a nivell arqueològic, que entre la segona meitat del segle II i el darrer terç del segle IV s’abandonaren pacíficament gairebé la meitat dels establiments agrícoles permet plantejar una nova explicació
Josep Maria Nolla Brufau
doaj   +1 more source