Results 41 to 50 of about 1,825,190 (283)

A case study of choroideremia carrier – Use of multi-spectral imaging in highlighting clinical features

American Journal of Ophthalmology Case Reports, 2016
Purpose: To report the use of non-invasive multi-spectral imaging of a female choroideremia (CHM) carrier with mild visual symptoms and extensive fundus mottling. Observation: This was an observational case report study.
Pravin U. Dugel, Cheryl N. Zimmer, Ayda M. Shahidi   +2 more
doaj   +1 more source

Multimodal imaging of hereditary retinal dystrophies (a series of clinical cases)

Российский офтальмологический журнал, 2020
Multimodal visualization data of inherited retinal degeneration (IRD) on a Mirante platform (Nidek, Japan), used in a number of clinical cases, is compared with the data obtained by electrophysiological diagnostic methods.
S. V. Milash, I. V. Zolnikova, V. V. Kadyshev   +2 more
doaj   +1 more source

Large‐scale Whole‐Exome Sequencing Defines the Protein‐Coding Architecture of Retinal Structure, Visual Function, and Major Blinding Diseases

Advanced Science, EarlyView.
Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li, Yijun Ge, Jingxiao Du, Liu Yang, Bangsheng Wu, Chenyue Hang, Mengxi Shen, Yimin Mao, Ting Zhang, Qiyu Bo, Tianyuan Zhao, Yutian Jiao, Yazhi Wang, Shunxiang Gao, Jieqiong Chen, Junran Sun, Tong Li, Huixun Jia, Yang Dou, Wei Cheng, Xiaoling Wan, Jintai Yu, Xiaodong Sun, Bai Lu   +23 more
wiley   +1 more source

Idiopathic unilateral vortex vein dilation: a multimodal imaging case report

BMC Ophthalmology
Purpose To report a case of idiopathic vortex vein dilatation diagnosed using multimodal imaging, including indocyanine green angiography (ICGA), sodium fluorescein angiography (FFA), wide-angle color fundus photography, fundus autofluorescence (FAF ...
Xiaohui Tian, Leibing Ji, Reyisai Abudulamu   +2 more
doaj   +1 more source

MULTIMODAL FUNDUS IMAGING OF PSEUDOXANTHOMA ELASTICUM

Retina, 2011
PURPOSE: To investigate spectral domain optical coherence tomography and autofluorescence findings in eyes with pseudoxanthoma elasticum. METHODS: A retrospective analysis of visual acuity, spectral domain optical coherence tomography, and autofluorescence findings of consecutive patients with pseudoxanthoma elasticum was performed. The spectral domain
Zweifel, S A, Imamura, Y, Freund, K B, Spaide, R F   +3 more
openaire   +3 more sources

A Population-Based Ultra-Widefield Digital Image Grading Study for Age-Related Macular Degeneration-Like Lesions at the Peripheral Retina. [PDF]

, 2015
Our understanding of the relevance of peripheral retinal abnormalities to disease in general and in age-related macular degeneration (AMD) in particular is limited by the lack of detailed peripheral imaging studies.
Lengyel, Imre, Florea, D, Lengyel, I, Csutak, Adrienne, Peto, Tunde, Peto, T, Leung, I, Bird, AC, Florea, Daniela, Csutak, A, Bird, Alan C., Jonasson, Fridbert, Leung, Irene, Jonasson, F   +13 more
core   +1 more source

An Aggregation‐Induced Polymerization Poly(Disulfide)‐Drug Nanoplatform for Autoimmune Uveitis Therapy via Inhibiting the cGAS‐STING Pathway

Advanced Science, EarlyView.
A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu, Wenbo Geng, Qinjin Dai, Wanyun Zhang, Yuxian Lai, Pei Zhang, Chunjiang Zhou, Yinuo Wang, Qingfeng Cao, Xiang Luo, Yujie Lai, Changwei Huang, Peizeng Yang   +12 more
wiley   +1 more source

Fundus retinal image analyses for screening and diagnosing diabetic retinopathy, macular edema, and glaucoma disorders

, 2020
This chapter shadows light over the fundamental imaging techniques used in the field of ophthalmology; namely fundus retinal imaging. Since it is a noninvasive way of imaging the retina, the method is popular among the ophthalmic community and the ...
Chalakkal, Renoh, Renoh Johnson Chalakkal, Hong, SC, Waleed Habib Abdulla, Sheng Chiong Hong, Abdulla, Waleed   +5 more
core   +1 more source

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

Automatic Detection of Microaneurysms in Fundus Images

International Journal of Software Innovation, 2022
Early detection and treatment of diabetic retinopathy can delay blindness and improve quality of life for diabetic patients. It is difficult to detect early symptoms of diabetic retinopathy, which is presented by few microaneurysms in fundus images. This study proposes an algorithm to detect microaneurysms in fundus images automatically.
Jesús Eduardo Ochoa Astorga, Linni Wang, Shuhei Yamada, Yusuke Fujiwara, Weiwei Du, Yahui Peng   +5 more
openaire   +1 more source