Results 201 to 210 of about 1,386,309 (382)

Hydrogen‐Deuterium Exchange Mass Spectrometry for Molecular Glue Characterization

open access: yesAdvanced Science, EarlyView.
Molecular glues that stabilize protein–protein interactions are challenging to identify. Here, hydrogen‐deuterium exchange mass spectrometry can show and reveal gluing mechanisms that vary between protein binding partners. Abstract Molecular glues are powerful bioactive molecules that stabilize protein–protein interactions.
Danielle F. Kay   +3 more
wiley   +1 more source

Enhancing the β‐Oxidation‐Like Pathway for the Optimal Production of the Immunosuppressant Mycophenolic Acid

open access: yesAdvanced Science, EarlyView.
The most elaborate known example of β‐oxidation‐like pathway recruitment in fungi is reported, involving a 10‐step oxidative chain‐shortening cascade catalyzed by five dedicated enzymes to generate the pharmacophore of mycophenolic acid (MPA)—a novel clinical immunosuppressant. Our findings illustrate how nature repurposes catabolic enzymes for complex
Baoqiang Fan   +5 more
wiley   +1 more source

Expansion of maltose/sucrose related transporters in Ascomycetes and their association with corresponding disaccharide utilization

open access: yesCurrent Research in Microbial Sciences
Sugar transporters (STs) play a crucial role in mediating sugar uptake in fungi and have been increasingly studied due to their important biological roles and industrial potential.
Li Xu   +4 more
doaj  

Shifu‐Inspired Fungal Paper Yarns

open access: yesAdvanced Science, EarlyView.
Fungal chitin‐β‐glucan sheets, processed using Shifu techniques, yield yarns with tunable strength and mechanical properties matching or surpassing cotton and viscose. Chemical modification and hybridization routes enable further property control.
Anne Zhao   +3 more
wiley   +1 more source

Photocontrolled Release of Urea Enables the Detection of Urea–Urease Intermediates by Cryo‐FTIR

open access: yesAngewandte Chemie, EarlyView.
Urease is a fast enzyme, presenting kcat of the order of 103–104 s−1. To enable the visualization of its mechanism we explored the technique of cryo‐FTIR. By means of using a ruthenium complex as a caged‐urea, upon light irradiation urea was released and we could see the coordination of the urea to the active site.
Caterina G.C. Marques Netto   +7 more
wiley   +2 more sources

Electronic Nanomaterials for Plants: A Review on Current Advances and Future Prospects

open access: yesAdvanced Electronic Materials, EarlyView.
Global food security faces mounting challenges from climate change and rapid population growth. This review highlights the pivotal role of electronic nanomaterials–including metals, metal oxides, and carbon‐based structures–in enhancing plant photosynthesis, nutrient uptake, and stress resilience. Furthermore, it explores how emerging platforms such as
Ciro Allará   +8 more
wiley   +1 more source

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