Results 211 to 220 of about 1,386,309 (382)

FUNGAL GENETICS [PDF]

open access: yesAnnual Review of Genetics, 1968
openaire   +2 more sources

Supramolecular Assembly of Triterpenoids: Current State and Biomedical Perspectives

open access: yesAggregate, EarlyView.
Triterpenoids serve as both exceptional molecular motifs for supramolecular assembly and versatile therapeutic agents, offering broad biological functions to improve health outcomes and enhance treatment efficacy. This review comprehensively summarizes recent advances in triterpenoid‐based supramolecular systems, including their roles as functional ...
Jie Zhong   +3 more
wiley   +1 more source

Structural Basis for a Scaffolding Role of the COM Domain in Nonribosomal Peptide Synthetases

open access: yesAngewandte Chemie, EarlyView.
COM domains are known as docking domains between subunits of nonribosomal peptide synthetases (NRPSs). Here, the first structure of a fused, internal COM domain with its neighboring domains is reported. Structural, biochemical and crosslinking data show that COM domains play an unexpected role in properly positioning epimerization (E) and condensation (
Julia Diecker   +7 more
wiley   +2 more sources

Investigating Social Immunity in Swarming Locusts via a Triple Animal–Robot–Pathogen Hybrid Interaction

open access: yesAdvanced Intelligent Systems, EarlyView.
This study explores social immunity in gregarious locusts using a groundbreaking animal–robot–pathogen interaction model. By comparing locust responses to biomimetic agents mimicking healthy and infected individuals, significant behavioral changes are revealed.
Donato Romano, Cesare Stefanini
wiley   +1 more source

Solid‐State NMR Reveals Reorganization of the Aspergillus fumigatus Cell Wall Due to a Host‐Defence Peptide

open access: yesAngewandte Chemie, EarlyView.
Understanding the mode of action is critical to develop new antifungal drugs. Solid‐state NMR was used to study the reorganization of the Aspergillus fumigatus cell wall by a host‐defence peptide. We identified specific polysaccharides and amino acids that are affected by the peptide.
Ajit Kumar Bishoyi   +5 more
wiley   +2 more sources

Fungal Ribotoxins

open access: yes, 2018
Fungal ribotoxins constitute a family of extracellular ribonucleases with exquisite specificity against rRNA (ribonucleic acid). They induce apoptotic death of cells after inhibiting protein translation. Ribosomes become functionally incompetent because ribotoxins cleave one single phosphodiester bond, located at a unique and universally conserved loop,
García Ortega, Lucía   +2 more
openaire   +1 more source

Mainstream Artificial Intelligence Technologies in Contemporary Ophthalmology

open access: yesAdvanced Intelligent Systems, EarlyView.
This review explores the latest artificial intelligence (AI) technologies in ophthalmology, focusing on four key data types: medical imaging, electronic health records, robotic‐assisted surgery, and genomics. It examines the structural features, use cases, clinical goals, and evaluation metrics of various AI algorithms, while also introducing emerging ...
Shiqi Yin   +9 more
wiley   +1 more source

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