Results 11 to 20 of about 19,745 (223)

Fungal dysbiosis: immunity and interactions at mucosal barriers. [PDF]

Nat Rev Immunol, 2017
(Uploaded by Plazi for the Bat Literature Project) The term dysbiosis has been used to describe disruptions of microbial communities that lead to a shift in steady-state composition that is distinct from that induced by infections. Recent work has suggested that, in addition to bacterial dysbiosis, fungal dysbiosis might contribute to the pathology of ...
Iliev ID, Leonardi I.
europepmc   +6 more sources

Fungal gut microbiota dysbiosis in systemic lupus erythematosus

Frontiers in Microbiology, 2023
IntroductionDespite recent developments in our comprehension of how the gut microbiota and systemic lupus erythematosus (SLE) are related. The mycobiome: which is a small but crucial part of the gut microbiota and is involved in hosts’ homeostasis and ...
Ping Yang, Rui Xu, Fei Chen, Shanshan Chen, Adeel Khan, Liang Li, Xiaoshan Zhang, Yanbo Wang, Zhipeng Xu, Han Shen   +9 more
doaj   +3 more sources

Fungal Dysbiosis Correlates with the Development of Tumor-Induced Cachexia in Mice. [PDF]

J Fungi (Basel), 2020
ABSTRACTCachexia (CC) is a devastating metabolic syndrome associated with a series of underlying diseases that greatly affects life quality and expectancy among cancer patients. Studies involving mouse models, in which CC was induced through inoculation with tumor cells, originally suggested the existence of a direct correlation between the development
Jabes DL, de Maria YNLF, Aciole Barbosa D, Santos KBNH, Carvalho LM, Humberto AC, Alencar VC, Costa de Oliveira R, Batista ML, Menegidio FB, Nunes LR.   +10 more
europepmc   +6 more sources

Fungal dysbiosis following antibacterial monotherapy in canine otitis externa. [PDF]

J Small Anim Pract
ObjectivesTo evaluate evidence of Malassezia overgrowth following successful topical antibacterial monotherapy of refractory canine bacterial otitis using semi‐quantitative cultures.Materials and MethodsTwenty‐nine dogs with bacterial otitis were treated topically with either fluoro‐quinolone [0.5% enrofloxacin (18 dogs, 19 treatment events, 25 ears ...
Juhola J, Brennan E, Ferguson EA, Loeffler A, Hendricks A, Frosini SM, Chang YM, Bond R.   +7 more
europepmc   +3 more sources

Glucocorticoid-Induced Leucine Zipper Protein and Yeast-Extracted Compound Alleviate Colitis and Reduce Fungal Dysbiosis [PDF]

Biomolecules
Inflammatory bowel diseases (IBD) have a complex, poorly understood pathogenesis and lack long-lasting effective treatments. Recent research suggests that intestinal fungal dysbiosis may play a role in IBD development. This study investigates the effects
Marco Gentili, Samuele Sabbatini, Emilia Nunzi, Eleonora Lusenti, Luigi Cari, Antonella Mencacci, Nathalie Ballet, Graziella Migliorati, Carlo Riccardi, Simona Ronchetti, Claudia Monari   +10 more
doaj   +2 more sources

Gut mycobiota dysbiosis and an emergent state of “co-dysbiosis” are associated with IgE sensitization in children with comorbid allergic rhinitis and constipation [PDF]

Frontiers in Immunology
BackgroundThe comorbidity of allergic rhinitis (AR) and functional constipation (FC), termed ARFC, implies shared gut–immune pathways. Although bacterial dysbiosis has been implicated, the role of the gut mycobiota (fungal community) in this specific ...
Haiying Liu, Liqing Liang, Chunyan Wang, Rongrong Luo, Qiuhua Luo, Congfu Huang   +5 more
doaj   +2 more sources

Fungal Dysbiosis in Mucosa-associated Microbiota of Crohn's Disease Patients. [PDF]

J Crohns Colitis, 2016
Gut microbiota is involved in many physiological functions and its imbalance is associated with several diseases, particularly with inflammatory bowel diseases. Mucosa-associated microbiota could have a key role in induction of host immunity and in inflammatory process. Although the role of fungi has been suggested in inflammatory disease pathogenesis,
Liguori G, Lamas B, Richard ML, Brandi G, da Costa G, Hoffmann TW, Di Simone MP, Calabrese C, Poggioli G, Langella P, Campieri M, Sokol H.   +11 more
europepmc   +5 more sources

Oral fungal dysbiosis and systemic immune dysfunction in Chinese patients with schizophrenia. [PDF]

Transl Psychiatry
Oral microbial dysbiosis contributes to the development of schizophrenia (SZ). While numerous studies have investigated alterations in the oral bacterial microbiota among SZ patients, investigations into the fungal microbiota, another integral component of the oral microbiota, are scarce.
Liu X, Ling Z, Cheng Y, Wu L, Shao L, Gao J, Lei W, Zhu Z, Ding W, Song Q, Zhao L, Jin G.   +11 more
europepmc   +4 more sources

Intraneoplastic fungal dysbiosis is associated with colorectal cancer progression and host gene mutation. [PDF]

EBioMedicine
The relationship between intraneoplastic fungi and colorectal cancer (CRC) progression remains largely unclear. Here, we investigated fungal community changes in adenoma and CRC and their correlation with host genetic mutations.We obtained 261 tissue biopsies from two geographically distinct cohorts of CRC and adenoma patients, with each individual ...
Yuan K, Xu H, Li S, Coker OO, Liu W, Wang L, Zhang X, Yu J.   +7 more
europepmc   +3 more sources

Neglected kingdoms: the gut virome, mycobiome and their role in inflammatory bowel disease [PDF]

Gut Microbes
Inflammatory bowel disease (IBD) is a chronic relapsing-remitting disorder of the gastrointestinal tract characterized by immune dysregulation, epithelial barrier dysfunction, and microbial imbalance.
Yashar Houshyar, Fan Zhang, Paris Tavakoli, Michael C. Grimm, Georgina L. Hold   +4 more
doaj   +2 more sources