Results 11 to 20 of about 13,270 (230)

Immunological Consequences of Intestinal Fungal Dysbiosis [PDF]

Cell Host and Microbe, 2016
Compared to bacteria, the role of fungi within the intestinal microbiota is poorly understood. In this study we investigated whether the presence of a "healthy" fungal community in the gut is important for modulating immune function. Prolonged oral treatment of mice with antifungal drugs resulted in increased disease severity in acute and chronic ...
JOSÉ J Limon, Matthew Gargus, Hanlin L Wang   +2 more
exaly   +8 more sources

Fungal dysbiosis predicts the diagnosis of pediatric Crohn's disease. [PDF]

World J Gastroenterol, 2018
To investigate the accuracy of fungal dysbiosis in mucosa and stool for predicting the diagnosis of Crohn's disease (CD).Children were prospectively enrolled in two medical centers: one university hospital and one private gastroenterology clinic in the city of Riyadh, Kingdom of Saudi Arabia.
El Mouzan MI, Korolev KS, Al Mofarreh MA, Menon R, Winter HS, Al Sarkhy AA, Dowd SE, Al Barrag AM, Assiri AA.   +8 more
europepmc   +6 more sources

Fungal microbiota dysbiosis in IBD [PDF]

Gut, 2016
Objective The bacterial intestinal microbiota plays major roles in human physiology and IBDs. Although some data suggest a role of the fungal microbiota in IBD pathogenesis, the available data are scarce. The aim of our study was to characterise the faecal fungal microbiota in patients with IBD.
Sokol, Harry, Leducq, Valentin, Aschard, Hugues, Pham, Hang-Phuong, Jegou, Sarah, Landman, Cecilia, Cohen, David, Liguori, Giuseppina, Bourrier, Anne, Nion-Larmurier, Isabelle, Cosnes, Jacques, Seksik, Philippe, Langella, Philippe, Skurnik, David, Richard, Mathias L, Beaugerie, Laurent   +15 more
openaire   +7 more sources

Fungal Microbiota Dysbiosis and Ecological Alterations in Gastric Cancer

Frontiers in Microbiology, 2022
Changes in bacteriome composition have a strong association with gastric cancer (GC). However, the relationship between stomach fungal microbiota composition and human host immune factors remains largely unknown. With high-throughput internal transcribed
Ping Yang, Xiaoshan Zhang, Xiaoshan Zhang, Rui Xu, Rui Xu, Khan Adeel, Khan Adeel, Xiaofeng Lu, Min Chen, Han Shen, Zhiyang Li, Zhipeng Xu   +11 more
doaj   +3 more sources

Tryptophan metabolism and bacterial commensals prevent fungal dysbiosis in Arabidopsis roots. [PDF]

Proc Natl Acad Sci U S A, 2021
Significance Understanding how host–microbe homeostasis is controlled and maintained in plant roots is key to enhance plant productivity. However, the factors that contribute to the maintenance of this equilibrium between plant roots and their multikingdom microbial communities remain largely unknown.
Wolinska KW, Vannier N, Thiergart T, Pickel B, Gremmen S, Piasecka A, Piślewska-Bednarek M, Nakano RT, Belkhadir Y, Bednarek P, Hacquard S.   +10 more
europepmc   +8 more sources

Fungal dysbiosis in cirrhosis

Gut, 2017
Objective Cirrhotics have a high rate of infections, which are increasingly fungal or culture-negative in nature. While infected cirrhotics have bacterial dysbiosis, the role of fungi is unclear. We aimed to evaluate gut bacterial and fungal dysbiosis in cross-sectional and longitudinal analyses of outpatient and ...
Jasmohan S, Bajaj, Eric J, Liu, Raffi, Kheradman, Andrew, Fagan, Douglas M, Heuman, Melanie, White, Edith A, Gavis, Phillip, Hylemon, Masoumeh, Sikaroodi, Patrick M, Gillevet   +9 more
openaire   +3 more sources

Oral fungal dysbiosis and systemic immune dysfunction in Chinese patients with schizophrenia. [PDF]

Transl Psychiatry
Oral microbial dysbiosis contributes to the development of schizophrenia (SZ). While numerous studies have investigated alterations in the oral bacterial microbiota among SZ patients, investigations into the fungal microbiota, another integral component of the oral microbiota, are scarce.
Liu X, Ling Z, Cheng Y, Wu L, Shao L, Gao J, Lei W, Zhu Z, Ding W, Song Q, Zhao L, Jin G.   +11 more
europepmc   +5 more sources

The Role of the Cutaneous Mycobiome in Atopic Dermatitis

Journal of Fungi, 2022
Atopic dermatitis is a chronic inflammatory skin disorder characterized by eczematous lesions, itch, and a significant deterioration in the quality of life.
Milena Szczepańska, Leszek Blicharz, Joanna Nowaczyk, Karolina Makowska, Mohamad Goldust, Anna Waśkiel-Burnat, Joanna Czuwara, Zbigniew Samochocki, Lidia Rudnicka   +8 more
doaj   +2 more sources

Fungal Dysbiosis Correlates with the Development of Tumor-Induced Cachexia in Mice. [PDF]

J Fungi (Basel), 2020
ABSTRACT Cachexia (CC) is a devastating metabolic syndrome associated with a series of underlying diseases that greatly affects life quality and expectancy among cancer patients. Studies involving mouse models, in which CC was induced through inoculation with tumor cells, originally suggested the existence of a direct
Jabes DL, de Maria YNLF, Aciole Barbosa D, Santos KBNH, Carvalho LM, Humberto AC, Alencar VC, Costa de Oliveira R, Batista ML, Menegidio FB, Nunes LR.   +10 more
europepmc   +7 more sources

Fungal gut microbiota dysbiosis in systemic lupus erythematosus

Frontiers in Microbiology, 2023
IntroductionDespite recent developments in our comprehension of how the gut microbiota and systemic lupus erythematosus (SLE) are related. The mycobiome: which is a small but crucial part of the gut microbiota and is involved in hosts’ homeostasis and ...
Ping Yang, Rui Xu, Fei Chen, Shanshan Chen, Adeel Khan, Liang Li, Xiaoshan Zhang, Yanbo Wang, Zhipeng Xu, Han Shen   +9 more
doaj   +3 more sources