Results 161 to 170 of about 3,817,565 (379)

Toward the consensus of definitions for the phenomena of antifungal tolerance and persistence in filamentous fungi

open access: yesmBio
Antifungal drug tolerance and persistence are being increasingly recognized in fungal pathogens. Accordingly, more and more research is being carried out to characterize and understand these phenomena. However, the terminology and methodology employed in
Jorge Amich   +3 more
doaj   +1 more source

Effect of Bacterial Endotoxin on Experimental Fungal Infections [PDF]

open access: bronze, 1968
Harry R. Kimball   +2 more
openalex   +1 more source

A Novel nor@DHB Matrix for Direct Microbial Analysis in Lung Cancer Tissues

open access: yesAdvanced Science, EarlyView.
Integrated matrix‐assisted laser desorption/ionization mass spectrometry workflow quantifies intratumoral microbes in lung cancer through lipopolysaccharide/lipid A extraction from biopsies. The novel ionic matrix called norharmane conjugated to 2,5‐dihydroxybenzoic acid enhances lipid A ionization, enabling direct detection of bacterial genera ...
Liang Shan   +12 more
wiley   +1 more source

Exo‐Selective Intramolecular (4+3) Cycloadditions to Trans‐Fused Perhydroazulenes: An Asymmetric Formal Synthesis of (−)‐Pseudolaric Acid B

open access: yesAngewandte Chemie, EarlyView.
We present an asymmetric formal synthesis of pseudolaric acid B, for which we developed a new family of substrates with an epoxide geminally tethered to a sidechain bearing a furan, which undergoes a TESOTf‐catalyzed intramolecular (4+3) cycloaddition to yield the trans‐fused perhydroazulene core and the requisite quaternary stereocenter of the natural
Zengsheng Yin   +7 more
wiley   +2 more sources

Post‐Translational Modifications of TOE3 Regulate Antiviral Defense in Tobacco

open access: yesAdvanced Science, EarlyView.
CK2αL phosphorylates TOE3 and enhances its stability, while FBXL1 promotes the ubiquitination‐degradation of TOE3 via the 26S proteasome. Compared to CK2αL‐phosphorylated TOE3, nonphosphorylated TOE3 shows a much higher affinity for FBXL1 and is more susceptible to ubiquitination‐degradation, thus facilitating viral infection. The regulatory mechanisms
Bolei Jiao   +3 more
wiley   +1 more source

In vitro interactions of berbamine hydrochloride and azoles against Aspergillus fumigatus

open access: yesMicrobiology Spectrum
The growing resistance of Aspergillus to azoles poses a significant challenge in treating invasive fungal infections. This study aimed to investigate the synergistic effect of berbamine hydrochloride (BBM) combined with azoles in treating Aspergillus ...
Heng Zhang   +6 more
doaj   +1 more source

Fatal fungal infection following open-heart surgery. [PDF]

open access: bronze, 1967
S.W.B. Newsom   +2 more
openalex   +1 more source

Impact of Virus‐Mediated Modifications in Bacterial Communities on the Accumulation of Soil Organic Carbon

open access: yesAdvanced Science, EarlyView.
This study illustrates the impact of viruses on carbon cycling in soils with different availabilities of carbon. In conditions of low carbon availability, viruses adopt a lysogenic lifestyle, integrate into the host genomes and facilitate the degradation of carbon.
Mingfeng Liu   +8 more
wiley   +1 more source

Polymorphic α‐Glucans as Structural Scaffolds in Cryptococcus Cell Walls for Chitin, Capsule, and Melanin: Insights From 13C and 1H Solid‐State NMR

open access: yesAngewandte Chemie, EarlyView.
Cryptococcus neoformans cell wall α‐1,3‐glucans as dual anchors for melanin and capsule: Solid‐state NMR of intact C. neoformans cells reveals five forms of α‐1,3‐glucans that structurally bridge melanin and capsule layers. These polysaccharides interact with chitin, chitosan, and β‐glucans to create a molecular scaffold that underlies virulence and ...
Ankur Ankur   +11 more
wiley   +2 more sources

Peptide Hormone‐Mediated Regulation of Plant Development and Environmental Adaptability

open access: yesAdvanced Science, EarlyView.
In this review, recent advances in understanding the roles of plant peptide hormones in regulating growth, reproduction, and environmental adaptability are systematically summarized. It further elucidates the challenges in studying these peptides, such as their low abundance, functional redundancy, and complex signaling mechanisms, and highlights their
Xin Li   +8 more
wiley   +1 more source

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