Results 11 to 20 of about 231,884 (249)
CYP51 Paralogue Structure Is Associated with Intrinsic Azole Resistance in Fungi
mBio, 2021 Azole antifungals are the main treatment for fungal disease in humans. Many species are intrinsically resistant to azoles—in other words all members of the species are resistant without prior exposure—and we do not understand why.
N. Van Rhijn +3 more
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mBio, 2022 Aspergillosis, in its various manifestations, is a major cause of morbidity and mortality. Very few classes of antifungal drugs have been approved for clinical use to treat these diseases and resistance to the first-line therapeutic class, the triazoles ...
Norman van Rhijn +8 more
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Microbiology Spectrum, 2022 Filamentous fungi form multicellular hyphae, which generally form pellets in liquid shake cultures, during the vegetative growth stage. Because of these characteristics, growth-monitoring methods commonly used in bacteria and yeast have not been applied ...
Ken Miyazawa +4 more
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Detrimental impact of the IL-33/ST2 axis in an animal infection model with Cryptococcus neoformans
Allergology International, 2023 Cryptococcus neoformans and Cryptococcus gattii are pathogenic fungi that infect the human respiratory system and cause life-threatening pulmonary cryptococcosis.
Keigo Ueno, Yoshitsugu Miyazaki
doaj +1 more source
Journal of Fungi, 2021 Human activities have significantly impacted the environment and are changing our climate in ways that will have major consequences for ourselves, and endanger animal, plant and microbial life on Earth.
Norman van Rhijn, Michael Bromley
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Journal of Fungi, 2022 Fungal infections of the eye continue to be an important cause of ocular morbidity and loss of vision, particularly in the developing world [...]
Max Carlos Ramírez-Soto +1 more
openaire +3 more sources
Frontiers in Cellular and Infection Microbiology, 2022 Damage to the lung epithelium is a unifying feature of disease caused by the saprophytic fungus Aspergillus fumigatus. However, the mechanistic basis and the regulatory control of such damage is poorly characterized.
Sayema Rahman +10 more
doaj +1 more source
Courtship Ritual of Male and Female Nuclei during Fertilization in Neurospora crassa
Microbiology Spectrum, 2021 Sexual reproduction is a key process influencing the evolution and adaptation of animals, plants, and many eukaryotic microorganisms, such as fungi.
Sylvain Brun +4 more
doaj +1 more source
Ca2+ Signalling Differentially Regulates Germ-Tube Formation and Cell Fusion in Fusarium oxysporum
Journal of Fungi, 2022 Fusarium oxysporum is an important plant pathogen and an emerging opportunistic human pathogen. Germination of conidial spores and their fusion via conidial anastomosis tubes (CATs) are significant events during colony establishment in culture and on ...
Smija M. Kurian +2 more
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Pathogenicity and virulence of Aspergillus fumigatus
Virulence, 2023 Pulmonary infections caused by the mould pathogen Aspergillus fumigatus are a major cause of morbidity and mortality globally. Compromised lung defences arising from immunosuppression, chronic respiratory conditions or more recently, concomitant viral or
Kayleigh Earle +7 more
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