Results 51 to 60 of about 438,844 (285)
Immunotherapy of invasive fungal infection in hematopoietic stem cell transplant recipients [PDF]
, 2013 Despite the availability of new antifungal compounds, invasive fungal infection remains a significant cause of morbidity and mortality in children and adults undergoing allogeneic hematopoietic stem cell transplantation (HSCT). Allogeneic HSCT recipients
Klingebiel, Thomas +3 more
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic +6 more
wiley +1 more source
Homeostatic control of an iron repressor in a GI tract resident
eLife, 2023 The transition metal iron plays a crucial role in living cells. However, high levels of iron are potentially toxic through the production of reactive oxygen species (ROS), serving as a deterrent to the commensal fungus Candida albicans for colonization ...
Yuanyuan Wang +16 more
doaj +1 more source
Epizootiology of the Fungal Pathogen, \u3ci\u3eZoophthora Phytonomi\u3c/i\u3e (Zygomycetes: Entomophthorales) in Field Populations of Alfalfa Weevil (Coleoptera: Curculionidae) Larvae in Illinois [PDF]
, 2017 The influence of the fungal pathogen, Zoophthora phytonomi, on larvae of the alfalfa weevil, Hypera postica, was studied in three alfalfa fields in Illinois. Disease epizootics occurred in all three fields and disease onset was ob- served within a fairly
Armbrust, Edward J +3 more
core +2 more sources
mBio, 2017 Secondary metabolites are key mediators of virulence for many pathogens. Aspergillus fumigatus produces a vast array of these bioactive molecules, the biosynthesis of which is catalyzed by nonribosomal peptide synthetases (NRPSs) or polyketide synthases (
Anna Johns +14 more
doaj +1 more source
Proceedings of the American Thoracic Society, 1992 Increased travel and outdoor leisure activities place the elderly individual at risk for infection with the endemic mycoses, histoplasmosis, blastomycosis, coccidioidomycoses, and sporotrichosis. Elderly patients who are immunosuppressed are at risk for infection with the opportunistic fungi such as Candida and Aspergillus.
openaire +3 more sources
Archives of Disease in Childhood, 1989 The dermatophyte or ringworm infections are confined to stratum corneum or keratinised structures derived from epidermis, such as nail or hair, and these superficial infections are considered in this chapter. The natural course of infection is variable and in many instances spontaneous remission occurs.
openaire +2 more sources
Advanced Functional Materials, EarlyView.Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou +11 more
wiley +1 more source
Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals
Advanced Functional Materials, EarlyView.This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee +4 more
wiley +1 more source
mBio, 2020 Aspergillus fumigatus can cause a variety of lung diseases in immunocompromised patients, including life-threatening invasive aspergillosis. There are only three main classes of antifungal drugs currently used to treat aspergillosis, and antifungal ...
Robert-Jan Bleichrodt +4 more
doaj +1 more source