Results 141 to 150 of about 261,513 (310)
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva +8 more
wiley +1 more source
Changing epidemiology of invasive fungal infections : focus on HIV/AIDS patients
, 2009 The epidemiology of invasive fungal infections (IFI) in HIV/AIDS patients has changed profoundly since the introduction of highly active antiretroviral therapy (HAART) at the end of 1996. Early initiation of HAART with reversal of severe immunodeficiency
S. Antinori
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British Journal of Clinical Pharmacology, EarlyView.Abstract Aim The aim of this systematic review was to assess all available clinical data regarding the use of a single dose of basiliximab in solid organ transplantation compared to the standard double dosage, with particular interest in efficacy, safety and cost‐savings.
Alessio Provenzani +4 more
wiley +1 more source
, 2015 Ahmet SoysalDivision of Pediatric Infectious Diseases, Department of Pediatrics, Faculty of Medicine, Marmara University, Istanbul, TurkeyAbstract: Posaconazole is a triazole antifungal agent that has broad-spectrum activity against many yeasts and ...
Soysal A
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British Journal of Clinical Pharmacology, EarlyView.Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk +5 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Voriconazole is commonly used to prevent fungal infections after haematopoietic stem cell transplantation (HSCT). Although its metabolism is influenced by CYP2C19 genetics and inflammation, their combined effect is rarely considered in clinical practice, and integrated analyses remain limited.
Sylvia D. Klomp +6 more
wiley +1 more source
, 2018 Marco Fiore,1,* Marco Cascella,2,* Sabrina Bimonte,2 Alberto Enrico Maraolo,3 Ivan Gentile,3 Vincenzo Schiavone,4 Maria Caterina Pace1 1Department of Anaesthesiological, Surgical and Emergency Sciences, University of Campania “Luigi Vanvitelli ...
Cascella M +6 more
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Cutaneous fungal infections predominantly caused by dermatophytes are a global concern. These infections vary widely by region, age, and body site, with recent shifts in the pathogen distribution.
Anna Lyakhovitsky +6 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Introduction Active surveillance of adverse events using healthcare data is emerging as complementary to the monitoring of spontaneous reports and stand‐alone pharmacoepidemiologic studies. The risk of urinary tract infections (UTIs) was listed as a special warning for sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) when marketed in Europe
Haoxin Le +5 more
wiley +1 more source
New Strategies to Combat Human Fungal Infections
Over the past few decades, numerous reports have highlighted the significant rise in fungal infections worldwide, contributing to considerable morbidity, mortality, and escalating healthcare costs [...
Marta Helena Branquinha +1 more
core +1 more source