Results 71 to 80 of about 261,513 (310)

Addressing Microbial Resistance Worldwide: Challenges over Controlling Life-Threatening Fungal Infections

, 2023
Fungal infections are a serious global concern because of their ability to spread and colonize host tissues in immunocompromised individuals. Such infections have been frequently reported worldwide and are currently gaining clinical research relevance ...
Caroline Patini Rezende, Leonardo Martins-Santana, Antonio Rossi, Fausto Almeida, Nilce Maria Martinez-Rossi   +4 more
core   +1 more source

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units : protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project [PDF]

, 2019
The reliability of diagnostic criteria for invasive fungal diseases (IFD) developed for severely immunocompromised patients is questionable in critically ill adult patients in intensive care units (ICU).
Vazquez, J.A., Martin-Loeches, I., Garnacho-Montero, J, Rello, J., Timsit, JF, Muñoz, P, Arıkan Akdagli, S, Calandra, T., Alastruey-Izquierdo, A, Azoulay, E, Koehler, P, Vazquez, JA, De Waele, J.J., Arikan-Akdagli, S., Bassetti, M, Rebuffi, C, Dimopoulos, G., Cornely, O, Blot, Stijn, Poulakou, G, Hoenigl, M, Rebuffi, C., Lass-Flörl, C., Kullberg, BJ, Blot, S.I., de Lange, D.W., Koehler, P., Kullberg, B.J., De Waele, Jan, Grecchi, C, Grecchi, C., Azoulay, E., Zuccaro, V, Taccone, FS, Garnacho-Montero, J., Maertens, J, Torres, A, Alastruey-Izquierdo, A., Cuenca-Estrella, M, Hoenigl, M., Taccone, F.S., Righi, E., Muñoz, P., Kanj, SS, Scudeller, L, Poulakou, G., Kanj, S.S., Sanguinetti, M., De Rosa, FG, Akova, M., Torres, A., Martin-Loeches, I, Lamoth, F, De Rosa, F.G., Timsit, J.F., Sanguinetti, M, Lamoth, F., Maertens, J., Calandra, T, Cornely, O.A., Scudeller, L., Akova, M, Agvald-Ohman, C., Lass-Flörl, C, Zuccaro, V., Giacobbe, D.R., Dimopoulos, G, Agvald-Ohman, C, Righi, E, de Lange, DW, Giacobbe, DR, Rello, J, Bassetti, M., Cuenca-Estrella, M.   +73 more
core   +1 more source

Rapid Genomic Diagnosis of Fungal Infections in the Age of Next-Generation Sequencing

, 2021
Next-generation sequencing (NGS) technologies have recently developed beyond the research realm and started to mature into clinical applications. Here, we review the current use of NGS for laboratory diagnosis of fungal infections.
Jade L. L. Teng, Susanna K. P. Lau, Chi-Ching Tsang, Patrick C. Y. Woo   +3 more
core   +1 more source

Hijacking the Host Clock: A Nematode Effector Antagonizes Soybean Circadian Defense and Translation Control

Advanced Science, EarlyView.
Soybean employs its circadian clock, governed by GmCCA1, to rhythmically defend against soybean cyst nematodes. The pathogen retaliates by secreting the effector Hg4E02, which hijacks the clock to suppress defense and co‐opt the host's translation machinery for nutrient acquisition.
Xingwei Wang, Yufeng Xu, Yanfei Hu, Lijun Cao, Ru Jiang, Changtian Chen, Rick Masonbrink, Thomas Maier, Yuchen Tu, Yabo Shi, Enhui Liu, Lingan Kong, Chan Guo, Wei Zhao, Peng Shi, Wenzhen Du, Andrew Severin, Thomas Baum, Deliang Peng, Huan Peng, Mian Zhou, Wei Wang   +21 more
wiley   +1 more source

Impact of interventions to reduce nosocomial transmission of SARS-CoV-2 in English NHS Trusts: a computational modelling study

BMC Infectious Diseases
Background Prior to September 2021, 55,000–90,000 hospital inpatients in England were identified as having a potentially nosocomial SARS-CoV-2 infection. This includes cases that were likely missed due to pauci- or asymptomatic infection.
Stephanie Evans, James Stimson, Diane Pople, Peter J White, Mark H Wilcox, Julie V Robotham   +5 more
doaj   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

A Keratinocyte‐Mast Cell NF‐κB2/CXCL2/IL‐6 Amplification Loop Enhances Cutaneous Antifungal Defense Against C. albicans

Advanced Science, EarlyView.
ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan, Manyun Mao, Jiaan Zhang, Zhimin Duan, JiaNing Wang, Yujie Chen, Sihan Chen, Chuting Liang, Xvyue Zhou, Songmei Geng, Min Li, Xu Chen, Ni Lian   +12 more
wiley   +1 more source

Invasive fungal infections in Chile: a multicenter study of fungal prevalence and susceptibility during a 1-year period [PDF]

, 2004
During the first year of an ongoing surveillance program of invasive fungal infections (IFI) a total of 130 patients (56% male) with fungal strains isolated from blood and other sterile sites were reported from 13 hospitals in Chile.
Díaz Jarabrán, María Cristina, Silva Vargas, Víctor, Chilean Invasive Fungal Infections Group, Febré V., Naldy   +3 more
core  

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source