Results 121 to 130 of about 729,622 (302)

Exploiting the behaviour of wild malaria vectors to achieve high infection with fungal biocontrol agents [PDF]

, 2012
Background Control of mosquitoes that transmit malaria has been the mainstay in the fight against the disease, but alternative methods are required in view of emerging insecticide resistance.
Kirby, Matthew J, Mpingwa, Monica W, Mpingwa, M W, Russell, T, Koenraadt, C J M, Koenraadt, Constantianus J M, Lyimo, Issa N, Lyimo, I.N., Mpingwa, M. W., Mpingwa Monica W, Lwetoijera, Dickson W., Nchimbi, Nuru, Takken, W., Mpingwa, M.W., Mnyone, Ladslaus L, Hancock Penelope A, Mnyone, L L, Koenraadt, C.J.M., Hancock, P.A., Nchimbi, N, Hancock, Penelope A, Takken, Willem, Lwetoijera, D. W., Nuru Nchimbi, Koenraadt, C. J. M., Hancock, P A, Koenraadt, Constantianus JM, Lyimo Issa N, Russell Tanya L, Lwetoijera Dickson W, Issa N Lyimo, Koenraadt Constantianus JM, Nchimbi Nuru, Kirby, M.J., Willem Takken, Mnyone, L. L., Hancock, Penelope A., Kirby, Matthew J., Matthew J Kirby, Lwetoijera, D W, Mnyone, Ladslaus L., Kirby Matthew J, Mpingwa, Monica W., Lwetoijera, D.W., Hancock, P. A., Constantianus JM Koenraadt, Koenraadt, Constantianus J.M., Koenraadt, Constantianus J. M., Takken, W, Ladslaus L Mnyone, Russell, T. L., Lyimo, Issa N., Tanya L Russell, Mnyone Ladslaus L, Dickson W Lwetoijera, Lwetoijera, Dickson W, Kirby, M. J., Penelope A Hancock, Takken Willem, Lyimo, I N, Lyimo, I. N., Monica W Mpingwa, Kirby, M J, Mnyone, L.L., Nchimbi, N., Mnyone, Ladslaus, Russell, Tanya L, Russell, T.L., Russell, Tanya L.   +68 more
core   +1 more source

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

Advanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song, Can Zhao, Qiaoling Wang, Hongjiao Zhang, Xiao Liu, Linqi Wang, Michael Bromley, Wen‐Bing Yin   +7 more
wiley   +1 more source

Genome-wide functional annotation of Phomopsis longicolla isolate MSPL 10-6

Genomics Data, 2016
Phomopsis seed decay of soybean is caused primarily by the seed-borne fungal pathogen Phomopsis longicolla (syn. Diaporthe longicolla). This disease severely decreases soybean seed quality, reduces seedling vigor and stand establishment, and suppresses ...
Omar Darwish, Shuxian Li, Benjamin Matthews, Nadim Alkharouf   +3 more
doaj   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Cellular responses of Candida albicans to phagocytosis and the extracellular activities of neutrophils are critical to counteract carbohydrate starvation, oxidative and nitrosative stress [PDF]

, 2012
Acknowledgments We thank Alexander Johnson (yhb1D/D), Karl Kuchler (sodD/D mutants), Janet Quinn (hog1D/D, hog1/cap1D/D, trx1D/D) and Peter Staib (ssu1D/D) for providing mutant strains.
Kurzai, Oliver, Hanna Windecker (108562), Windecker Hanna, Iryna M. Bohovych, Christine Dunker (108560), Dunker Christine, Alistair J. P. Brown (108565), Pedro Miramón, Bohovych, Iryna M, Pedro Miramón (108557), Alistair J. P. Brown, Iryna M. Bohovych (108563), Kurzai Oliver, Oliver Kurzai, Dunker, Christine, Alistair J P Brown, Iryna M Bohovych, Christine Dunker, Miramón, Pedro, Bernhard Hube (108571), Hube Bernhard, Brown, Alistair J P, Bernhard Hube, Oliver Kurzai (108568), Hube, Bernhard, Miramón Pedro, Bohovych Iryna M., Brown Alistair J. P., Hanna Windecker, Windecker, Hanna   +29 more
core   +1 more source

Tarımsal Üretimde Yararlanılan Trichoderma Ürünleri ve Metabolitleri

International Journal of Secondary Metabolite, 2017
Fitopatojenik ajanların sebep olduğu bitki hastalıklarıyla, önemli ölçüde ürün kayıpları meydana gelmektedir. Dünya üzerindeki birçok ülkede,  tarımda pestisit uygulamalarını ve bağımlılığını azaltacak, tüketici ve çevre güvenliğini arttıracak yasal ...
EVRİM ÖZKALE
doaj   +1 more source

Symbiont‐Induced HSP83 Establishes Two‐Tiered Control of Antifungal Immunity in an Invasive Beetle–Fungus Complex

Advanced Science, EarlyView.
In an invasive beetle–fungus complex, the mutualist Leptographium procerum induces host HSP83 and modulates Toll‐dependent antifungal immunity. HSP83 mediates two‐tiered control by associating with selected fungal recognition receptors and restraining Dorsal‐driven antimicrobial peptide transcription.
Qingtai Yang, Zhudong Liu, Yuqiao Yin, Jing Su, Dunyang Yu, Longsheng Xing, Zhen Zou, Le Kang, Jianghua Sun   +8 more
wiley   +1 more source

Selection and orchard testing of antagonists suppressing conidia production of the apple scab pathogen Venturia inaequalis [PDF]

, 2009
Apple scab caused by Venturia inaequalis is a major disease in apple production. Epidemics in spring are initiated by ascospores produced on overwintering leaves whereas epidemics during summer are driven by conidia produced on apple leaves by biotrophic
Molhoek, W.M.L., Köhl, J., Goossen-van de Geijn, H.M., Groenenboom-de Haas, B.H.   +3 more
core   +1 more source

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

Advanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao, Markus Isfeld Diehl, Caroline N. Jones   +2 more
wiley   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

Angewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma, Komal Sharma, Anku Sharma, Kamya Rao, Rahul Jain, Brett VanVeller   +5 more
wiley   +2 more sources