Results 131 to 140 of about 778,294 (303)
Arthritis &Rheumatology, EarlyView.Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia +16 more
wiley +1 more source
IgG Glycosylation‐Dependent CLEC7A Signaling Drives Podocyte Dysfunction in Lupus Nephritis
Arthritis &Rheumatology, EarlyView.Objective Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE) that can lead to end‐stage kidney disease and increased mortality. IgG from patients with LN displays abnormal glycosylation, contributing to podocyte injury.
Rohit Upadhyay +3 more
wiley +1 more source
Admixture in the fungal pathogen Blastomyces
GENETICSAbstract Blastomyces is an emerging primary fungal pathogen that affects patients worldwide. The evolutionary processes that have resulted in the current diversity in the genus remain largely unexplored. We used whole-genome sequences from 99 Blastomyces isolates, including 2 sequenced in this study using long-read technologies, to infer
Gaston I Jofre +6 more
openaire +3 more sources
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Global warming and industrial pollutants pose significant threats to environmental sustainability. In response, enzymes have emerged as promising tools for mitigating pollution. Enzymatic hydrolysis is considered environmentally sustainable due to its biological nature.
Gustavo Marques Serra +4 more
wiley +1 more source
Candida tropicalis Spontaneous Fungal Peritonitis in a Patient with Liver Cirrhosis: A Case Report
Case Reports in GastroenterologyIntroduction: Spontaneous fungal peritonitis is a less common yet serious complication of liver cirrhosis with high mortality rates. Awareness of spontaneous fungal peritonitis may improve patient outcomes by increasing early identification ...
Adam Rushford +4 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk +5 more
wiley +1 more source
Pathogen diversity, epidemiology and control of sclerotinia disease in vegetable crops [PDF]
Sclerotinia sclerotiorum is a necrotrophic fungal pathogen with a worldwide distribution and a wide host range, including many economically important crops. The control strategies for this pathogen and related species include using fungicides, biological
Warmington, Rachel Julie
core
British Journal of Clinical Pharmacology, EarlyView.Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar +6 more
wiley +1 more source
Cell death outcomes following fungal pathogen attack.
, 2013 Depending on the genotypes of both the plant host and the fungal invader, any one of several cell death pathways can be activated. Although these pathways intersect in cell death, they culminate in disparate outcomes, immunity, or disease as detailed in ...
Martin B. Dickman (215370) +1 more
core +1 more source