In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Developmental Regulation of an Adhesin Gene during Cellular Morphogenesis in the Fungal Pathogen Candida albicans [PDF]
Peer ...
Argimon, Silvia +35 more
core +1 more source
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Biocommunication of Fungal Organisms [PDF]
The development and growth of fungal organisms depend on successful communication processes (a) within the organism and between organisms, (b) with the same or related species and (c) with non-related organisms.
Guenther Witzany
core
Fungal biofilm resistance [PDF]
Fungal biofilm infections have become increasingly recognised as a significant clinical problem. One of the major reasons behind this is the impact that these have upon treatment, as antifungal therapy often fails and surgical intervention is required ...
Ramage, Gordon +7 more
core +1 more source
Sphingolipid Signaling in Fungal Pathogens [PDF]
Sphingolipid involvement in infectious disease is a new and exciting branch of research. Various microbial pathogens have been shown to synthesize their own sphingolipids and some have evolved methods to "hijack" host sphingolipids for their own use. For instance, Sphingomonas species are bacterial pathogens that lack the lipopolysaccharide component ...
Ryan, Rhome, Maurizio, Del Poeta
openaire +2 more sources
Human Pegivirus Encephalitis With Brain Detection and Response to Sofosbuvir Ledipasvir
ABSTRACT Human pegivirus (HPgV‐1) has been associated with severe encephalomyelitis in immunocompromised patients. Its neurological spectrum remains poorly defined. We report a slowly progressive encephalitis in a person living with well‐controlled HIV, characterized by white matter abnormalities and inflammatory cerebrospinal fluid (CSF). HPgV RNA was
Antoine Moulignier +3 more
wiley +1 more source
Comparative genomics yields insights into niche adaptation of plant vascular wilt pathogens [PDF]
The vascular wilt fungi Verticillium dahliae and V. albo-atrum infect over 200 plant species, causing billions of dollars in annual crop losses. The characteristic wilt symptoms are a result of colonization and proliferation of the pathogens in the ...
Katherine F Dobinson +127 more
core +1 more source
Characterization of the strawberry pathogen Gnomonia fragariae, and biocontrol possibilities [PDF]
The strawberry root rot complex or black root rot is common and increasing problem in perennial strawberry plantings worldwide. In many cases the causes of root rot are not detected or it is referred to several pathogens.
Moročko, Inga
core +1 more source
Enhancing the precision diagnosis and treatment of HIV-related coinfections through metagenomic next-generation sequencing [PDF]
Aim: Because of severe immunosuppression, coinfections continue to be a major cause of morbidity and mortality in HIV-infected patients. As the primary method currently used for diagnosing coinfections in HIV-infected patients, conventional ...
Yun-Meng Yan +10 more
doaj +1 more source

