Results 1 to 10 of about 645,117 (180)

Botrytis cinerea Transcription Factor BcXyr1 Regulates (Hemi-)Cellulase Production and Fungal Virulence [PDF]

mSystems, 2022
Botrytis cinerea is an agriculturally notorious plant-pathogenic fungus with a broad host range. During plant colonization, B. cinerea secretes a wide range of plant-cell-wall-degrading enzymes (PCWDEs) that help in macerating the plant tissue, but their
Liang Ma, Tong Liu, Ke Zhang, Haojie Shi, Lei Zhang, Gen Zou, Amir Sharon   +6 more
doaj   +3 more sources

Natural compounds from freshwater mussels disrupt fungal virulence determinants and influence fluconazole susceptibility in the presence of macrophages in Cryptococcus neoformans [PDF]

Microbiology Spectrum
Cryptococcus neoformans is a human fungal pathogen responsible for fatal infections, especially in patients with a depressed immune system. Overexposure to antifungal drugs due to prolonged treatment regimens and structure-similar applications in ...
Davier Gutierrez-Gongora, Michael Woods, Ryan S. Prosser, Jennifer Geddes-McAlister   +3 more
doaj   +3 more sources

Autophagy Regulates Fungal Virulence and Sexual Reproduction in Cryptococcus neoformans [PDF]

Frontiers in Cell and Developmental Biology, 2020
Autophagy (macroautophagy) is an evolutionarily conserved degradation pathway involved in bulk degradation of cytoplasmic organelles, old protein, and other macromolecules and nutrient recycling during starvation.
Su-Ting Jiang, Su-Ting Jiang, An-Ni Chang, Lian-Tao Han, Lian-Tao Han, Jie-Shu Guo, Jie-Shu Guo, Yuan-Hong Li, Yuan-Hong Li, Tong-Bao Liu, Tong-Bao Liu   +10 more
doaj   +3 more sources

Molecular Mechanisms of Pathogenic Fungal Virulence Regulation by Cell Membrane Phospholipids [PDF]

Journal of Fungi
Pathogenic fungi represent a growing concern for human health, necessitating a deeper understanding of their molecular mechanisms of virulence to formulate effective antifungal strategies.
Yitong Li, Hongchen Wang, Hengxiu Wang, Tianming Wang, Daqiang Wu, Wenfan Wei   +5 more
doaj   +3 more sources

Editorial: Fungal virulence [PDF]

Frontiers in Fungal Biology
Jaime David Acosta-España, Jaime David Acosta-España, Jaime David Acosta-España, Jaime David Acosta-España, Jaime David Acosta-España, Antonio José de Jesus Evangelista, Antonio José de Jesus Evangelista, Antonio José de Jesus Evangelista, Jonathas Sales de Oliveira, Rosana Serpa, Rosana Serpa   +10 more
doaj   +3 more sources

Ubiquitination of acetyltransferase Gcn5 contributes to fungal virulence in Fusarium graminearum. [PDF]

mBio, 2023
The histone acetyltransferase general control non-depressible 5 (Gcn5) plays a critical role in the epigenetic landscape and chromatin modification for regulating a wide variety of biological events.
Chen A, Zhou Y, Ren Y, Liu C, Han X, Wang J, Ma Z, Chen Y.   +7 more
europepmc   +2 more sources

Mitochondrial prohibitin complex regulates fungal virulence via ATG24-assisted mitophagy. [PDF]

Commun Biol, 2022
Prohibitins are highly conserved eukaryotic proteins in mitochondria that function in various cellular processes. The roles of prohibitins in fungal virulence and their regulatory mechanisms are still unknown.
Yan Y, Tang J, Yuan Q, Liu C, Chen X, Liu H, Huang J, Bao C, Hsiang T, Zheng L.   +9 more
europepmc   +2 more sources

Cbp1, a fungal virulence factor under positive selection, forms an effector complex that drives macrophage lysis. [PDF]

PLoS Pathog, 2022
Intracellular pathogens secrete effectors to manipulate their host cells. Histoplasma capsulatum (Hc) is a fungal intracellular pathogen of humans that grows in a yeast form in the host.
Azimova D, Herrera N, Duvenage L, Voorhies M, Rodriguez RA, English BC, Hoving JC, Rosenberg O, Sil A.   +8 more
europepmc   +2 more sources

Role of F-box Protein Cdc4 in Fungal Virulence and Sexual Reproduction of Cryptococcus neoformans. [PDF]

Front Cell Infect Microbiol, 2021
Cryptococcus neoformans is an opportunistic yeast-like pathogen that mainly infects immunocompromised individuals and causes fatal meningitis. Sexual reproduction can promote the exchange of genetic material between different strains of C.
Wu T, Fan CL, Han LT, Guo YB, Liu TB.
europepmc   +2 more sources

Proteome and secretome profiling of zinc availability in Cryptococcus neoformans identifies Wos2 as a subtle influencer of fungal virulence determinants. [PDF]

BMC Microbiol, 2021
Background Fungal infections impact over 25% of the global population. For the opportunistic fungal pathogen, Cryptococcus neoformans , infection leads to cryptococcosis.
Ball B, Woroszchuk E, Sukumaran A, West H, Afaq A, Carruthers-Lay D, Muselius B, Gee L, Langille M, Pladwig S, Kazi S, Hendriks A, Geddes-McAlister J.   +12 more
europepmc   +2 more sources