ABSTRACT Autophagy and the ubiquitin/26S proteasome system (UPS) play critical roles in the immune defence of the host against pathogen invasion. As a countermeasure, pathogens deploy effector proteins to subvert or hijack autophagy and UPS processes.
Yaqian Shi +7 more
wiley +1 more source
Exploring the interaction between endornavirus and <i>Sclerotinia sclerotiorum</i>: mechanisms of phytopathogenic fungal virulence and antivirus. [PDF]
Mu F +7 more
europepmc +1 more source
LUCID: An Integrative Approach for Target Discovery and dsRNA Design in Plant Fungal Pathogens
LUCID: A computational pipeline for RNAi‐based biofungicide design. ABSTRACT Phytopathogenic fungi pose an escalating threat to global food security and ecosystem stability, as resistance and environmental concerns diminish the effectiveness of conventional fungicides.
Lucía Jiménez‐Castro +4 more
wiley +1 more source
FGSE02, a Novel Secreted Protein in <i>Fusarium graminearum</i> FG-12, Leads to Cell Death in Plant Tissues and Modulates Fungal Virulence. [PDF]
Hao Z, Pan L, Xu J, Yu C, Li J, Luo L.
europepmc +1 more source
Extracellular Vesicles From Paracoccidioides brasiliensis Can Induce the Expression of Fungal Virulence Traits In Vitro and Enhance Infection in Mice. [PDF]
Octaviano CE, Abrantes NE, Puccia R.
europepmc +1 more source
H3K27me3‐Mediated Epigenetic Silencing of FgHMG1 Enables Fungal Host Immune Evasion
ABSTRACT Histone H3 lysine 27 trimethylation (H3K27me3) is essential for fungal pathogenicity, yet its contribution to pathogen–host interactions remains incompletely understood. Here, we profiled H3K27me3 dynamics in Fusarium graminearum during infection and identified 132 H3K27me3‐marked genes (FgHMGs).
Xiaozhen Zhao +17 more
wiley +1 more source
Phospho-code of a conserved transcriptional factor underpins fungal virulence. [PDF]
Yang J +10 more
europepmc +1 more source
ABSTRACT The development of dual‐target inhibitors represents a cost‐effective strategy for integrated pest management. Here, we report the first dual‐target inhibitors designed against the evolutionarily conserved domain of phytoene synthase (PSY), a key enzyme in carotenoid biosynthesis.
Di Zhang +11 more
wiley +1 more source
Omics-Based Comparison of Fungal Virulence Genes, Biosynthetic Gene Clusters, and Small Molecules in Penicillium expansum and Penicillium chrysogenum. [PDF]
Bartholomew HP +8 more
europepmc +1 more source
The histone chaperone HIR maintains chromatin states to control nitrogen assimilation and fungal virulence. [PDF]
Jenull S +15 more
europepmc +1 more source

