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DFVF: database of fungal virulence factors [PDF]

open access: yesDatabase, 2012
Fungal pathogens cause various diseases for plant and animal hosts. Despite the extensive impact of fungi on human health and life, the threats posed by emerging fungal pathogens are poorly understood. Specifically, there exist few fungal virulence gene databases, which prevent effective bioinformatics studies on fungal pathogens.
Lu, Tao, Yao, Bo, Zhang, Chi
openaire   +2 more sources

Comprehensive identification of lysine 2-hydroxyisobutyrylated proteins in Ustilaginoidea virens reveals the involvement of lysine 2-hydroxyisobutyrylation in fungal virulence.

open access: yesJournal of Integrative Plant Biology, 2021
Lysine 2-hydroxyisobutyrylation (Khib ) is a newly identified post-translational modification (PTM) that plays important roles in transcription and cell proliferation in eukaryotes. However, its function remains unknown in phytopathogenic fungi. Here, we
Xiaoyang Chen   +8 more
semanticscholar   +1 more source

Functions of fungal melanin beyond virulence [PDF]

open access: yesFungal Biology Reviews, 2017
Melanins are ancient biological pigments found in all kingdoms of life. In fungi, their role in microbial pathogenesis is well established; however, these complex biomolecules also confer upon fungal microorganisms the faculty to tolerate extreme environments such as the Earth's poles, the International Space Station and places contaminated by toxic ...
Radames J.B. Cordero, Arturo Casadevall
openaire   +2 more sources

Distinct Roles of Two DNA Methyltransferases from Cryphonectria parasitica in Fungal Virulence, Responses to Hypovirus Infection, and Viral Clearance

open access: yesmBio, 2021
Although relatively few in number, studies of DNA methylation have shown that fungal DNA methylation is implicated in development, genome integrity, and genome defense.
Yo-Han Ko   +3 more
semanticscholar   +1 more source

Precise Expression of Afmed15 Is Crucial for Asexual Development, Virulence, and Survival of Aspergillus fumigatus

open access: yesmSphere, 2020
The rise of drug resistance in fungal pathogens is becoming a serious problem owing to the limited number of antifungal drugs available. Identifying and targeting factors essential for virulence or development unique to fungal pathogens is one approach ...
Luyu Guan   +4 more
doaj   +1 more source

Candida albicans Inhibits Pseudomonas aeruginosa Virulence through Suppression of Pyochelin and Pyoverdine Biosynthesis. [PDF]

open access: yesPLoS Pathogens, 2015
Bacterial-fungal interactions have important physiologic and medical ramifications, but the mechanisms of these interactions are poorly understood.
Eduardo Lopez-Medina   +7 more
doaj   +1 more source

Amoeba predation of Cryptococcus: A quantitative and population genomic evaluation of the accidental pathogen hypothesis.

open access: yesPLoS Pathogens, 2023
The "Amoeboid Predator-Fungal Animal Virulence Hypothesis" posits that interactions with environmental phagocytes shape the evolution of virulence traits in fungal pathogens.
Thomas J C Sauters   +8 more
doaj   +1 more source

Stress-induced nuclear accumulation is dispensable for Hog1-dependent gene expression and virulence in a fungal pathogen [PDF]

open access: yes, 2017
The authors thank E. Veal for intellectual input. This work was funded by the UK Biotechnology and Biological Research Council [J.Q. BB/K016393/1; A.J.P.B.
Brown, Alistair J P   +4 more
core   +2 more sources

Candidalysin: From Mechanism of Action to Biomarker Development and Therapeutic Response [PDF]

open access: yesInnovations in Digital Health, Diagnostics, and Biomarkers, 2021
The incidence of systemic fungal infection is increasing, and millions of people around the world suffer from fungal infections. Candida albicans is one of the most frequently isolated fungal pathogens in clinical settings. As a polymorphic organism, the
Yao-Qi Chen   +3 more
doaj   +1 more source

Transcriptomic analyses reveal comprehensive responses of insect hemocytes to mycopathogen Beauveria bassiana, and fungal virulence-related cell wall protein assists pathogen to evade host cellular defense

open access: yesVirulence, 2020
Entomopathogenic fungi naturally infect insect hosts in environment. Fungal invasion and host immune defense are still in the progress of co-evolution. In this study, entomopathogenic fungus Beauveria bassiana and lepidopteran insect Galleria mellonella ...
Jin-Li Ding, Jia Hou, M. Feng, S. Ying
semanticscholar   +1 more source

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