Results 61 to 70 of about 645,266 (318)

LaeA, a Regulator of Morphogenetic Fungal Virulence Factors [PDF]

Eukaryotic Cell, 2005
ABSTRACT Opportunistic animal and plant pathogens, well represented by the genus Aspergillus , have evolved unique mechanisms to adapt to and avoid host defenses. Aspergillus fumigatus , an increasingly serious pathogen owing to ...
Jin Woo, Bok, S Arunmozhi, Balajee, Kieren A, Marr, David, Andes, Kristian Fog, Nielsen, Jens C, Frisvad, Nancy P, Keller   +6 more
openaire   +2 more sources

Vomocytosis: Too Much Booze, Base, or Calcium? [PDF]

, 2019
Macrophages are well known for their phagocytic activity and their role in innate immune responses. Macrophages eat non-self particles, via a variety of mechanisms, and typically break down internalized cargo into small macromolecules.
Aaron, Alvarez, Alvarez, Artavanis-Tsakonas, Bain, Ben-Abdallah, Bielska, Blackstock, Boya, Bryan, Burch, Chang, Charlier, Chen, Cheng, Chu, Circu, Cox, Davis, De Leon-Rodriguez, De Leon-Rodriguez, Denham, Di, Diamond, Doshi, Dragotakes, Drew, Erb-Downward, Erwig, Evans, Feldmesser, Franchi, Fu, Gilbert, Gordon, Guerra, Gustafson, Haka, Han, Henson, Heo, Hibbs, Hoag, Hommel, Huang, Hybiske, Iwasaki, Johnston, Kjos, Kleinschek, Kruskal, Kusner, Lei, Leopold Wager, Levitz, Levitz, Lim, Liu, Lévêque, Ma, Maderna, May, Milam, Mosser, Murdock, Murray, Myers, Müller, Nel, Nicola, Nunes, Okagaki, O’Meara, Pauwels, Qiu, Rajasingham, Russell, Samantaray, Santiago-Tirado, Singh, Smith, Stukes, Stukes, Swisher, Tucker, Vashi, Voelz, Vu, Vu, Walkey, Wang, Wang, Watkins, Weiss, Wormley, Wozniak, Yates, Yoshida, Zaragoza   +98 more
core   +2 more sources

Phenotypic and Molecular Biological Analysis of Polymycovirus AfuPmV-1M From Aspergillus fumigatus: Reduced Fungal Virulence in a Mouse Infection Model

Frontiers in Microbiology, 2020
The filamentous fungal pathogen Aspergillus fumigatus is one of the most common causal agents of invasive fungal infection in humans; the infection is associated with an alarmingly high mortality rate.
Azusa Takahashi-Nakaguchi, Erika Shishido, Misa Yahara, Syun-ichi Urayama, A. Ninomiya, Yuto Chiba, Kanae Sakai, Daisuke Hagiwara, H. Chibana, H. Moriyama, T. Gonoi   +10 more
semanticscholar   +1 more source

What Are the Functions of Chitin Deacetylases in Aspergillus fumigatus?

Frontiers in Cellular and Infection Microbiology, 2020
Deacetylation of chitin by chitin deacetylases (Cda) results in the formation of chitosan. Chitosan, a polymer of β1,4 linked glucosamine, plays multiple roles in the function of the fungal cell wall, including virulence and evasion of host immune ...
Isabelle Mouyna, Sarah Dellière, Anne Beauvais, Fabrice Gravelat, Fabrice Gravelat, Brendan Snarr, Brendan Snarr, Mélanie Lehoux, Caitlin Zacharias, Caitlin Zacharias, Yan Sun, Steven de Jesus Carrion, Eric Pearlman, Donald C. Sheppard, Donald C. Sheppard, Jean-Paul Latgé   +15 more
doaj   +1 more source

Basal rot of narcissus : understanding pathogenicity in fusarium oxysporum f. sp. narcissi [PDF]

, 2019
Fusarium oxysporum is a globally distributed soilborne fungal pathogen causing root rots, bulb rots, crown rots and vascular wilts on a range of horticultural plants. Pathogenic F.
Armitage, Andrew D., Clarkson, John P., Handy, Claire, Harrison, Richard J., Hulin, Michelle T., Jackson, Alison C., Taylor, Andrew   +6 more
core   +2 more sources

Phosphate Acquisition and Virulence in Human Fungal Pathogens [PDF]

Microorganisms, 2017
The ability of pathogenic fungi to acquire essential macro and micronutrients during infection is a well-established virulence trait. Recent studies in the major human fungal pathogens Candida albicans and Cryptococcus neoformans have revealed that acquisition of the essential macronutrient, phosphate, is essential for virulence.
Ikeh M, Ahmed Y, Quinn J
openaire   +4 more sources

Virulence- and signaling-associated genes display a preference for long 3′UTRs during rice infection and metabolic stress in the rice blast fungus [PDF]

, 2019
Generation of mRNA isoforms by alternative polyadenylation (APA) and their involvement in regulation of fungal cellular processes, including virulence, remains elusive.
Demuez, Marie, Marconi, Marco, Ortega-Campayo, Víctor, Rodríguez-Romero, Julio, Sesma, Ane, Wilkinson, Mark D.   +5 more
core   +1 more source

Aspergillus fumigatus enhances elastase production in pseudomonas aeruginosaco-cultures [PDF]

, 2015
In the cystic fibrosis (CF) lung the presence of bacteria and fungi in the airways promotes an inflammatory response causing progressive lung damage, ultimately leading to high rates of morbidity and mortality.
Kerr, Stephen, Lappin, David F., Mackay, William G., Rajendran, Ranjith, Ramage, Gordon, Smith, Karen, Williams, Craig   +6 more
core   +1 more source

Oxalic Acid as a Fungal Acaracidal Virulence Factor [PDF]

Journal of Medical Entomology, 2005
Cell-free culture supernatants of the entomopathogenic fungus Beauveria bassiana (Bals.) Vuillemin were able to induce mortality in several tick species, including adult Ambylomma americanum (L.), Ambylomma maculatum Koch, and Ixodes scapularis Say. Four lines of experimental evidence support the hypothesis that oxalic acid secretion by B.
Brett H, Kirkland, Asma, Eisa, Nemat O, Keyhani   +2 more
openaire   +2 more sources

Enzymes that Counteract Nitrosative Stress Promote Fungal Virulence [PDF]

Current Biology, 2003
Enzymes that protect cells from reactive oxygen species (superoxide dismutase, catalase, peroxidase) have well-established roles in mammalian biology and microbial pathogenesis. Two recently identified enzymes detoxify nitric oxide (NO)-related molecules; flavohemoglobin denitrosylase consumes NO, and S-nitrosoglutathione (GSNO) reductase metabolizes ...
de Jesús-Berrı́os, Marisol, Liu, Limin, Nussbaum, Jesse C., Cox, Gary M., Stamler, Jonathan S., Heitman, Joseph   +5 more
openaire   +2 more sources