Results 71 to 80 of about 645,266 (318)

The palmitoyl-CoA ligase Fum16 is part of a Fusarium verticillioides fumonisin subcluster involved in self-protection

mBio
Fusarium verticillioides produces the mycotoxin fumonisin B1 (FB1), which disrupts sphingolipid biosynthesis by inhibiting ceramide synthase and affects the health of plants, animals, and humans. The means by which F. verticillioides protects itself from
Fabio Gherlone, Katarina Jojić, Ying Huang, Sandra Hoefgen, Vito Valiante, Slavica Janevska   +5 more
doaj   +1 more source

Degradation of human kininogens with the release of kinin peptides by extracellular proteinases of Candida spp. [PDF]

, 2010
The secretion of proteolytic enzymes by pathogenic microorganisms is one of the most successful strategies used by pathogens to colonize and infect the host organism.
Ben Nasr A., Ben Nasr A., Bergmann S., Boskey E.R., Colman R.W., De Bernardis F., Frick I.M., Imamura T., Kaminishi H., Karkowska-Kuleta J., Koelsch G., Maeda H., Maruo K., Matsudaira P., Molla A., Tapper H., White T.C.   +16 more
core   +1 more source

Insects defend against fungal infection by employing microRNAs to silence virulence-related genes

Proceedings of the National Academy of Sciences of the United States of America, 2021
Significance The entomopathogenic fungus Beauveria bassiana can overcome insecticide resistance and represents a promising tool for controlling mosquitoes and other insect pests.
Yan Wang, Chunlai Cui, Guandong Wang, Yifei Li, Sibao Wang   +4 more
semanticscholar   +1 more source

Evaluating the lethal and pre-lethal effects of a range of fungi against adult Anopheles stephensi mosquitoes

Malaria Journal, 2012
Background Insecticide resistance is seriously undermining efforts to eliminate malaria. In response, research on alternatives to the use of chemical insecticides against adult mosquito vectors has been increasing.
Blanford Simon, Jenkins Nina E, Read Andrew F, Thomas Matthew B   +3 more
doaj   +1 more source

The Role of Oxidoreductase-Like Protein Olp1 in Sexual Reproduction and Virulence of Cryptococcus neoformans

Microorganisms, 2020
Cryptococcus neoformans is a basidiomycete human fungal pathogen causing lethal meningoencephalitis, mainly in immunocompromised patients. Oxidoreductases are a class of enzymes that catalyze redox, playing a crucial role in biochemical reactions.
Qi-Kun Yu, Lian-Tao Han, Yu-Juan Wu, Tong-Bao Liu   +3 more
doaj   +1 more source

CYP52X1, representing new cytochrome P450 subfamily, displays fatty acid hydroxylase activity and contributes to virulence and growth on insect cuticular substrates in entomopathogenic fungus Beauveria bassiana [PDF]

, 2012
Infection of insects by the entomopathogenic fungus Beauveria bassiana proceeds via attachment and penetration of the host cuticle. The outermost epicuticular layer or waxy layer of the insect represents a structure rich in lipids including abundant ...
Bernard, Grausem, Keyhani, Nemat O., Lesot, Agnes, Pedrini, Nicolás, Pinot, Franck, Widemann, Emilie, Zhang, Shizhu   +6 more
core   +2 more sources

Signal Transduction Cascades Regulating Fungal Development and Virulence [PDF]

Microbiology and Molecular Biology Reviews, 2000
SUMMARY Cellular differentiation, mating, and filamentous growth are regulated in many fungi by environmental and nutritional signals. For example, in response to nitrogen limitation, diploid cells of the yeast Saccharomyces cerevisiae undergo a dimorphic transition to filamentous growth referred to as pseudohyphal ...
K B, Lengeler, R C, Davidson, C, D'souza, T, Harashima, W C, Shen, P, Wang, X, Pan, M, Waugh, J, Heitman   +8 more
openaire   +2 more sources

Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach

Virulence, 2017
Increases in the incidence and mortality due to the major invasive fungal infections such as aspergillosis, candidiasis and cryptococcosis caused by the species of Aspergillus, Candida and Cryptococcus, are a growing threat to the immunosuppressed ...
P. R. Juvvadi, Soo Chan Lee, J. Heitman, W. Steinbach   +3 more
semanticscholar   +1 more source

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source

First report of Metarhizium anisopliae IP 46 pathogenicity in adult Anopheles gambiae s.s. and An. arabiensis (Diptera; Culicidae). [PDF]

, 2009
The entomopathogenic fungus Metarhizium anisopliae isolate IP 46, originating from a soil sample collected in 2001 in the Cerrado of Central Brazil, was tested for its ability to reduce the survival of adult male and female Anopheles gambiae s.s. and An.
Kirby, Matthew J, Luz, Christian, Lwetoijera, Dickson W, Lyimo, Issa N, Mnyone, Ladslaus L, Russell, Tanya L   +5 more
core   +6 more sources