Results 271 to 280 of about 1,109,640 (363)

Intranasal Wharton's Jelly‐Derived Mesenchymal Stem Cell Therapy, Alone or in Conjunction With Therapeutic Hypothermia, Alleviates Neonatal Hypoxic‐Ischemic Brain Injury in Mice

open access: yesAnnals of Neurology, EarlyView.
This study demonstrates that intranasal Wharton's jelly‐derived mesenchymal stem cell (WJ‐MSC) administration at 3 or 10 days post‐insult reduced the lesion size and sensorimotor impairment following neonatal hypoxic‐ischemic (HI) brain injury in mice. WJ‐MSCs expressed receptors for HI‐upregulated chemokines and migrated from the nasal cavity into the
Caroline G. M. de Theije   +9 more
wiley   +1 more source

Green Synthesis of Silver Nanoparticles: A Review of Polymer and Antimicrobial Drug Combinations for Enhanced Antimicrobial Applications

open access: yesAdvanced NanoBiomed Research, EarlyView.
Silver nanoparticles (AgNPs) synthesized using eco‐friendly green synthesis approaches exhibit remarkable antimicrobial activity and enhanced drug delivery potential. Polymer‐AgNPs conjugates further improve drug stability and targeted delivery, offering a multifunctional platform for biomedical applications.
Mukil Madhusudanan   +6 more
wiley   +1 more source

Decoding a Gut Commensal Signal: Structural and Immunological Profiling of Segatella Copri Lipopolysaccharide

open access: yesAngewandte Chemie, EarlyView.
The lipopolysaccharide (LPS) of Segatella copri is a structurally unique, immunomodulatory glycoconjugate. Combining mass spectrometry (MS), nuclear magnetic resonance (NMR), and cytometry by time‐of‐flight (CyTOF), we uncover a rough‐type LPS with reduced TLR4 agonism and selective monocyte effects, further highlighting the key role of LPS chemistry ...
Luca De Simone Carone   +17 more
wiley   +2 more sources

Mycophagy in Primates of the Issa Valley, Tanzania. [PDF]

open access: yesEcol Evol
Schulze TA   +7 more
europepmc   +1 more source

Silica Nanoparticles as Multifunctional Platforms for Vaccine Delivery and Immune Modulation in Infectious Diseases

open access: yesAdvanced NanoBiomed Research, EarlyView.
Overview of the use of silica nanoparticles in vaccines against pathogens. Different kinds of vaccines against infectious diseases are currently using solid or mesoporous silica nanoparticles in their formulation. Silica microparticles and nanoparticles (SiNPs) have been studied as vehicles for vaccines.
Noe Juvenal Mendoza‐Ramírez   +3 more
wiley   +1 more source

Gipsgärten: Selbstorganisierte röhrenförmige Strukturen aus Calciumsulfat mit Relevanz für die Suche nach außerirdischem Leben

open access: yesAngewandte Chemie, EarlyView.
Chemische Gärten sind selbstorganisierte abiotische Strukturen mit „lebensähnlichen” Formen. Hier zeigen wir, dass solche Prozesse auch nach Zugabe konzentrierter Sulfatlösungen zu festen Calciumsalzen ablaufen und sogenannte Gipsgärten ergeben. Die dafür nötigen Bedingungen sind weitgehend kompatibel mit den geochemischen Verhältnissen auf dem frühen ...
Selina Reigl   +5 more
wiley   +1 more source

Unravelling the Functional Diversity of Type III Polyketide Synthases in Fungi

open access: yesAngewandte Chemie, EarlyView.
Type III polyketide synthases (T3PKSs) produce diverse compounds of ecological and clinical importance. Here, the activity of 37 fungal T3PKSs was profiled, revealing unexpected products and generating several pharmaceutical precursors. The machine learning model trained on the activity data accurately extrapolates the predictions to other enzymes and ...
Nika Sokolova   +3 more
wiley   +2 more sources

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