The therapeutic efficacy of lipid nanoparticle(LNP)‐based drugs depends on endosomal escape. However, few methods are available for quantifying the efficiency of endosomal escape in vivo. Herein, a novel method for quantifying the endosomal escape efficiency index using magnetic resonance imaging is introduced.
Somin Lee+5 more
wiley +1 more source
A modular and customizable RNAi therapeutics delivery platform composed of a pseudosymmetric human RNA binding protein‐siRNA complex (SmiRNP) is developed. By fusing a targeting module and an endosomal escape peptide onto the delivery platform, SmiRNP successfully delivered siRNA to silence the KRAS oncogene in a colorectal carcinoma cell line, leading
Nok Yin Tam+9 more
wiley +1 more source
Cocksfoot (Dactylis glomerata L.) seed production : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science at Massey University [PDF]
Seed yield reduction due to variation in genotype, management, and incidence of diseases is common and well documented in grass seed crops. Two New Zealand cultivars (Grasslands Wana, Grasslands Kara) and two Japanese (Akimidori Makibamidori) cocksfoot ...
Zahid, Md Iqbal
core
Fungicide and Bactericide Effects on Carbon and Nitrogen Cycling in Soils: A Meta-Analysis
Fungi and bacteria play a central role in the cycling of carbon (C) and nitrogen (N), which has been frequently assessed by manipulating their abundance in soil with the application of fungicides and bactericides.
M. R. Ullah, F. Dijkstra
semanticscholar +1 more source
A dual‐vacancy‐engineered strategy is developed to construct Ga‐Zn co‐doped CuSe quantum dots (GZC QDs) via cation exchange using CuSe as a template. By precisely introducing Cu and Se vacancies, the optimized sample efficiently facilitates the selective photocatalytic oxidation of 5‐hydroxymethylfurfural (HMF) to 2,5‐diformylfuran (DFF), achieving an ...
Meijun Guo+6 more
wiley +1 more source
A study of seed vigour test methodology variables : a thesis presented in partial fulfilment of the requirements for the degree of Master of Applied Science in Seed Technology at Massey University [PDF]
Further research of some variables and procedures for promising seed vigour tests, such as the conductivity, Accelerated Ageing (AA) and Controlled Deterioration (CD) tests, is needed for their wider application and standardisation.
Zhang, Tao
core
Genotoxicity and Cytotoxicity Exerted by Pesticides in Different Biotic Matrices-An Overview of More Than a Decade of Experimental Evaluation [PDF]
Agrochemicals represent one of the most important sources of environmental pollution. Although attempts to reduce agrochemical use through organic agricultural practices and the use of other technologies to control pests continue, the problem is still
Larramendy, Marcelo Luis+3 more
core +2 more sources
Evaluation of Cell‐Extracellular Vesicle Interaction Using a Microfluidic Microsystem (CellExoChip)
A new microfluidic platform, the CellExoChip, reveals how cancer cells interact with exosomes to influence metastasis. This device isolates cancer cells and tracks their uptake exosomes and secretion of their exosomes in response to other exosomes. Lung cancer cells are showed preferentially absorb and respond to their own exosomes—hinting at a hidden ...
Nna‐Emeka Onukwugha+10 more
wiley +1 more source
Phytophthora infestans (P. infestans) is the causal agent of potato late blight, which caused the devastating Irish Potato Famine during 1845-1852. Until now, potato late blight is still the most serious threat to potato growth and has caused significant
Shumin Zhang+9 more
semanticscholar +1 more source
Hard‐Magnetic Soft Millirobots in Underactuated Systems
This review provides a comprehensive overview of hard‐magnetic soft millirobots in underactuated systems. It examines key advances in structural design, physics‐informed modeling, and control strategies, while highlighting the interplay among these domains.
Qiong Wang+4 more
wiley +1 more source