Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Advanced Healthcare Materials, EarlyView.Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Influence of methods of primary tillage and fungicides on the yield of spring barley
, 2022 E. N. Yakupov +4 more
openalex +2 more sources
Advanced Healthcare Materials, EarlyView.Photosensitizing lipid nanoparticles (PLNPs) are engineered by incorporating cholesterol–PEG–pheophorbide a into MC3‐based LNPs and encapsulating GPX4‐targeting siRNA. Upon light activation, PLNPs generate reactive oxygen species (ROS) while silencing GPX4 to induce ferroptosis.
Ga‐Hyun Bae +9 more
wiley +1 more source
A simulation program for the timing of fungicides to control Sooty Blotch in organic apple growing. First results in 2003 [PDF]
, 2004 A simulation program for infections by Sooty Blotch was developed based on literature data and expert judgements. The value of the model as tool for timing fungicide sprays to control Sooty Blotch was tested in 2003 in two randomized plot trials, and ...
Trapman, Marc
core
Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
Advanced Healthcare Materials, EarlyView.This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández +4 more
wiley +1 more source
Fungicide Resistance Genetics of Apple Scab fungus Venturia inaequalis [PDF]
, 2015 Apple scab, caused by the ascomycete fungus Venturia inaequalis, is considered the most devastating disease on domestic apple crops. Apples are the most important cultivated crop in temperate regions and the United States produced about 4.6 million tons ...
Reddel, Alexis LT
core +1 more source
Effective Management of Purple Blotch of Onion Caused by Alternaria porri (Ellis) Through Host Resistance, Fungicides and Botanicals [PDF]
, 2017 Priyanka Jhala +3 more
openalex +1 more source
Skin‐Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery
Advanced Healthcare Materials, EarlyView.This study presents an integrated skin‐interfaced device combining microfluidics, hydrogel film technology, flexible electronics, and iontophoresis‐based transdermal delivery of PDRN to enhance wound healing. The device effectively manages wound fluid, maintains optimal moisture, and non‐invasively delivers therapeutic drugs.
Dongjun Han +5 more
wiley +1 more source
Gradients of Aliveness and Engineering: A Taxonomy of Fungal Engineered Living Materials
Advanced Materials, EarlyView.This paper explores the potential of fungal engineered living materials (ELMs), examining fungal biology and growth mechanisms, which underpin their development. It presents a classification framework based on aliveness, scaffold composition, and engineering degree. Unique properties such as self‐healing, biosensing, and bioremediation are highlighted,
Elise Elsacker +5 more
wiley +1 more source