Results 131 to 140 of about 63,923 (289)

Mechanism‐Driven Screening of Membrane‐Targeting and Pore‐Forming Antimicrobial Peptides

Advanced Science, EarlyView.
To combat antibiotic resistance, this study employs mechanism‐driven screening with machine learning to identify pore‐forming antimicrobial peptides from amphibian and human metaproteomes. Seven peptides are validated, showing minimal toxicity and membrane disruption.
Jiaxuan Li, Chenguang Yang, Ruihan Dong, Juan Francisco Bada Juarez, Lei Wang, Maximilian Emanuel Wettstein, Dali Wang, Chan Cao, Ying Lu, Chen Song   +9 more
wiley   +1 more source

A Systematic Review on the Toxicology of European Union-Approved Triazole Fungicides in Cell Lines and Mammalian Models. [PDF]

J Xenobiot
Vulpe CB, Iachimov-Datcu AD, Pujicic A, Agachi BV.   +3 more
europepmc   +1 more source

Effects of Fertilizer and Fungicide Application Rates on the Incidence and Severity of Late Blight (<i>Phytophthora infestans</i>)<i> </i>on Irish Potatoes (<i>Solanum tuberosum </i>L) [PDF]

, 2017
Eric Mosota Rosana, Alex Machio Kange, Lenah Nakhone Wati, Daniel Otieno Otaye   +3 more
openalex   +1 more source

CACLENS: A Multitask Deep Learning System for Enzyme Discovery

Advanced Science, EarlyView.
CACLENS, a multimodal and multi‐task deep learning framework integrating cross‐attention, contrastive learning, and customized gate control, enables reaction type classification, EC number prediction, and reaction feasibility assessment. CACLENS accelerates functional enzyme discovery and identifies efficient Zearalenone (ZEN)‐degrading enzymes.
Xilong Yi, Yingzhu Tan, Huikang Lin, Guoqing Zhang, Ye Tian, Aibo Wu   +5 more
wiley   +1 more source

Non-chemical control of fungal pathogens in crops: a one-health perspective on strategies, mechanisms, and future directions. [PDF]

Front Plant Sci
Adkar-Purushothama CR, Chettimada A, Murali TS, Muthusamy A, Bouarab K, Perreault JP.   +5 more
europepmc   +1 more source

Synthetic Lethal Therapy Based on Dimorphism for Systemic Infection of Drug‐Resistant Candida albicans

Advanced Science, EarlyView.
To tackle the alarming mortality rate linked to Candida albicans infections, a synthetic lethal strategy precisely aimed at the two distinct forms of this fungus: yeast and hyphae is formulated. Ultimately, through the innovative use of macrophage membranes for drug delivery, the effectiveness of this strategy is substantially boosted while ...
Yang Gao, Jiahe Su, Jiawei Yuan, Qinyan Cao, Yue Wu, Yuyang Xiao, Guang Yang, Ruomu Xia, Jingpeng Yang, Yanan Li, Lina Wu, He Huang, Lingtong Meng   +12 more
wiley   +1 more source

Harnessing Nanoparticles and Nanosuspensions to Combat Powdery Mildew: A Frontier in Vegetable and Fruit Protection. [PDF]

J Fungi (Basel)
Geremew A, Shembo A, Carson L.
europepmc   +1 more source

Study the Effect of Plant Pathogenic Fungi in solid media in comparison with common Fungicide

, 2013
Khalid A. Habib, Rajaa A. Abbas, Haitham N. Ahmed   +2 more
openalex   +2 more sources

Pan2‐Pan3 Complex‐Mediated Deadenylation Enforces mRNA Quality Control for Infection of the Rice Blast Fungus

Advanced Science, EarlyView.
Discovery that deadenylation, rather than transcription, acts as the rate‐limiting step for developmental timing in a plant pathogen. Evidence that P‐body integrity and mRNA decay are mechanistically coupled to rapid cellular differentiation under environmental stress. Identification of Pan2‐Pan3 as a pathogen‐specific “meta‐virulence factor” absent in
Ziwei Lv, Junting Feng, Shenxian Zhou, Zhiguang Qu, Jun Peng, Xiao‐Lin Chen, Deng Chen   +6 more
wiley   +1 more source

Enhanced Pepper Resistance to <i>Sclerotium rolfsii</i> Through Root Development and Enzyme Modulation by Hexaconazole and Azoxystrobin. [PDF]

Plant Direct
Jia Y, Wen R, Liang C, Lan X, Mao T, Xing D, Lin W.   +6 more
europepmc   +1 more source