Results 41 to 50 of about 151,810 (328)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Impact of Exposure to Pyraclostrobin and to a Pyraclostrobin/Boscalid Mixture on the Mitochondrial Function of Human Hepatocytes

Molecules, 2023
Fungicides are widely used in agriculture for crop protection. Succinate dehydrogenase inhibitors (SDHIs) and strobilurins inhibit mitochondria electron transport chain (ETC) in fungi, by blocking complex II and complex III, respectively.
Mélina Carbone, Barbara Mathieu, Yasmine Vandensande, Bernard Gallez   +3 more
doaj   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Effects of Fungicides on Fungal Development, Conidiophore Morphology, and Conidial Releases from Single Strawberry Powdery Mildew Colonies Assessed Using an Electrostatic Technique

Agronomy
We evaluated the effects of fungicides on strawberry powdery mildew (PM) fungus, Podosphaera aphanis, using an electrostatic technique. Thirty-six fungicides were sprayed on single colonies of P.
Ami Takahara, Shunsuke Asano, Minami Kurokawa, Kanon Shibata, Rina Muto, Teruo Nonomura   +5 more
doaj   +1 more source

The Control of Stem Blight and the Spread of Potato Late Blight by Copper Seed Treatment [PDF]

, 2008
Late blight still is an unsolved problem in organic potato farming. Up to now the most effective way to control this disease is the use of copper fungicides. Transferring results from regular farming, seed treatments with copper fungicides shall postpone
Benker, Marianne, Keil, Sven, Zellner, Michael   +2 more
core  

Epidemiology and integrated control of Potato Late Blight in Europe [PDF]

, 2011
Phytophthora infestans, the causal agent of late blight, is a major threat to potato production in northwestern Europe. Before 1980, the worldwide population of P.
Andersson, B., Bain, R., Bradshaw, N., Cooke, R.J., Evenhuis, A., Hannukkala, A., Hansen, J.G., Hermansen, A., Kessel, G.J.T., Naerstad, R., Nielsen, B., Ritchie, F., Schepers, H.T.A.M., Shaw, D.S., Wander, J.G.N.   +14 more
core   +2 more sources

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Utilizing metabolomic approach to study the mode of action of fungicides and corresponding resistance in plant pathogens

Advanced Agrochem
Fungicides are an indispensable tool in plant disease control. Various modes of action (MOAs) have been identified in different fungicides to suppress plant pathogens.
Zhaochen Wu, Ziqi Liu, Zhihong Hu, Tingting Wang, Lijie Teng, Tan Dai, Pengfei Liu, Jianjun Hao, Xili Liu   +8 more
doaj   +1 more source

What Is the Role of Giant Endosomal Sorting Complexes Required for Transport (ESCRT) Structures in T Cell Activation?

Advanced Biology, EarlyView.
The article explores the discovery of unusually large, ring‐shaped ESCRT protein structures formed by immune and stromal cells. It investigates their formation, composition, and potential roles in immune synapse formation. The findings challenge assumptions about their function in immunological synapses, suggesting an exclusive role in maintaining ...
Anthi Psoma, Femmy C. Stempels, Rinse de Boer, Geert van den Bogaart   +3 more
wiley   +1 more source

Assessing the grey water footprint of pesticide use in the Mendoza wine region (Argentina): implications for sustainable water resources management

OENO One
This paper assesses the impact of viticulture on water resource quality in the Mendoza wine region using the grey water footprint (GWF) approach to estimate the amount of water required to dilute pesticides commonly used in local vineyards. Our analysis
Verónica Farreras, Belén Lana, Oscar Astorga   +2 more
doaj   +1 more source