Results 41 to 50 of about 56,557 (303)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Agrochemical protection practices for market gardeners and environmental risks on farms in Bouira (Northern Algeria) [PDF]

Glasnik Srpskog Geografskog Društva
Pesticides are used to protect crops against natural enemies. However, poor management of these products harms the environment and public health. The study aims to assess the use of pesticides on market garden crops in the Bouira region.
Bachouche Nassima, Lamri Naziha, Berghout Karima, Oultaf Lynda, Metna Ali Ahmed Fatiha, Bourfiss Nassima, Akkouche Saida   +6 more
doaj   +1 more source

Impact of Exposure to Pyraclostrobin and to a Pyraclostrobin/Boscalid Mixture on the Mitochondrial Function of Human Hepatocytes

Molecules, 2023
Fungicides are widely used in agriculture for crop protection. Succinate dehydrogenase inhibitors (SDHIs) and strobilurins inhibit mitochondria electron transport chain (ETC) in fungi, by blocking complex II and complex III, respectively.
Mélina Carbone, Barbara Mathieu, Yasmine Vandensande, Bernard Gallez   +3 more
doaj   +1 more source

The Evolution of Fungicide Resistance

, 2015
Fungicides are widely used in developed agricultural systems to control disease and safeguard crop yield and quality. Over time, however, resistance to many of the most effective fungicides has emerged and spread in pathogen populations, compromising disease control. This review describes the development of resistance using case histories based on four
Lucas, J. A., Hawkins, N. J., Fraaije, B. A.   +2 more
openaire   +2 more sources

Transfer Printing and Reconfiguration of Soft Electronics Using Digital Microfluidics and Laser Machining

Advanced Functional Materials, EarlyView.
This paper presents a digital microfluidics‐based technique for transferring and reconfiguring soft nanomembranes. Laser‐machined nanothin membranes are picked up, transported, and aligned via tailored surface tension and the actuation of water droplets, enabling the development of flexible electronics, the integration of functional materials on 3D ...
Quang Anh Nguyen, Chi Cong Nguyen, Tran Bach Dang, Phuoc Thien Phan, Jordan Thorpe, Michael Listyawan, Nhat Minh Doan, Sinuo Zhao, Hongru Chen, Trung Thien Hoang, Mingsheng Xu, Jisheng Han, Thanh Nho Do, Adam Hill, Timothée Mouterde, Hoang‐Phuong Phan   +15 more
wiley   +1 more source

Conformal Metallosaccharide Hybrid Films for Protecting Wood Surfaces From Environmental Damage

Advanced Functional Materials, EarlyView.
Ti‐ribose hybrid films fabricated by molecular layer deposition form a conformal and uniform coating on wood surfaces, which provides water repellence, dimensional stability, and resistance to acidic and alkaline environments, while preserving the natural appearance.
Wenwen Wang, Aranzazu Sierra Fernandez, Gabriele Botta, Evgenii Modin, Iva Šarić Janković, Shidong Ji, Junli Liu, Mato Knez   +7 more
wiley   +1 more source

The Effectiveness of Synthetic and Inorganic Substances in Different Apple Scab Control Strategies

Agriculture
A two-year trial (2021 and 2022) was performed with five different fungicide and foliar fertiliser application strategies to control apple scab (Venturia inaequalis) in integrated apple orchards in Latvia.
Regīna Rancāne, Alma Valiuškaitė, Laura Ozoliņa-Pole, Guna Bundzēna, Maksims Fiļipovičs, Neringa Rasiukevičiūtė   +5 more
doaj   +1 more source

The biochemical-mode of action of some newer azole fungicides

, 1993
The effects of the newer azole fungicides BAS 480F, flusilazole, and tebuconazole on growth and sterol composition of the plant pathogenic fungi Botrytis cinerea, Pyrenophora teres, Pyricularia oryzae, Rhynchosporium secalis, Ustilago maydis and Erysiphe
R. Thomas Loeffler, Iris M.‐Y. Kwok, Kwok, I. M. Y., Loeffler, R. T.   +3 more
core   +1 more source

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

Advanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa, Lineta Stonkute, Sara Trujillo, Mariana Azevedo Gonzalez Oliva, Francis Burton, Matthew J. Dalby, Oana Dobre, Godfrey Smith, Manuel Salmeron‐Sanchez   +8 more
wiley   +1 more source

Effects of Fungicides on Fungal Development, Conidiophore Morphology, and Conidial Releases from Single Strawberry Powdery Mildew Colonies Assessed Using an Electrostatic Technique

Agronomy
We evaluated the effects of fungicides on strawberry powdery mildew (PM) fungus, Podosphaera aphanis, using an electrostatic technique. Thirty-six fungicides were sprayed on single colonies of P.
Ami Takahara, Shunsuke Asano, Minami Kurokawa, Kanon Shibata, Rina Muto, Teruo Nonomura   +5 more
doaj   +1 more source