Results 81 to 90 of about 2,598 (200)

Reaction of diethyl phosphorisocyanatidite with 3,4-dichloro-5-hydroxy-2(5H)-furanone [PDF]

, 2000
Reaction of diethyl phosphorisocyanatidite with 3,4-dichloro-5-hydroxy-2(H)-furanone (mucochloric acid) is accomplished by mixing the reagents and leads to a bicyclic phosphonamidate.
Loginova I., Galkin V., Volodina Y., Sakhibullina V., Cherkasov R., Polezhaeva N.   +5 more
core  

Characterization Of Selective TRPM8 Ligands And Their Structure Activity Response (S.A.R) Relationship

Journal of Pharmacy & Pharmaceutical Sciences, 2010
PURPOSE: Transient receptor potential melastatin-8 (TRPM8) is an ion channel expressed extensively in sensory nerves, human prostate and overexpressed in a variety of cancers including prostate, breast, lung, colon and skin melanomas.
Muhammad Azhar Sherkheli, Angela K. Vogt-Eisele, Daniel Bura, Leopoldo R. Beltrán Márques, Günter Gisselmann, Hanns Hatt   +5 more
doaj   +1 more source

Furanone Derivatives from Terrestrial Streptomyces spp.

, 2012
Chemical investigation of the terrestrial Streptomyces sp. isolates GT2005/020 and ANK148 led to the isolation of two microbial furanone derivatives, 5-hydroxy-4-methylnaphtho[1,2-b]furan-3-one (1) and 4-hydroxy-5-methyl-furan-3-one (2), respectively ...
Schueffler, Anja, Laatsch, Hartmut, Arfan, Muhammad, Shaaban, Khaled Attia   +3 more
core  

Synthesis of 2(5H)-Furanone Derivatives with Symmetrical and Unsymmetrical Bis-1,2,3-triazole Structure

, 2014
The interesting bioactivities of 2(5H)-furanone, 1,2,3-triazole, and amino acid derivatives have promoted their combination into one multifunctional molecule.
Jianxiao Li (575512), Yuehe Tan (575511), Jingpei Huo (575513), Fuling Xue (538498), Zhaoyang Wang (395704)   +4 more
core   +1 more source

Neuroprotective furanones from a soil-derived fungus Penicillium paxilli ga254

Journal of Asian Natural Products Research
Three furanone derivatives (1–3), including one new compound, penicifuranone A (1), and one new natural product (2), along with one known dihydropyranone (4) were isolated from the solid rice medium fermentation of Penicillium paxilli ga254. The structures of these compounds were elucidated using comprehensive NMR spectroscopic analysis.
Guang, Li, Ya-Jing, Wang, Si-Qian, Zhou, Xiao-Qian, Wu, Jing, Li, Wen-Xuan, Wang, Hong-Ping, Long   +6 more
openaire   +2 more sources

2(5H)-Furanone Derivatives as Inhibitors of Staphylococcal Biofilms

, 2020
© 2016, Springer Science+Business Media New York.The opportunistic bacteria Staphylococcus aureus and Staphylococcus epidermidis often form rigid biofilms on wounds and artificial surfaces and thereby become extremely resistant to antimicrobials.
Trizna E., Latypova L., Kayumov A., Kurbangalieva A., Bogachev M.   +4 more
core  

Synthesis and Biological Properties of 2(5H)-Furanones Featuring Bromine Atoms on the Heterocyclic Ring and/or Brominated Substituents [PDF]

, 2017
This review deals with the synthesis of unnatural and natural 2(5H)-furanone derivatives featuring bromine atoms on the heterocyclic ring and/or brominated substituents, which have been described in the literature since 1951 up to February 2016.
ROSSI, RENZO, MARIANETTI, GIULIA, Chiara Manzini, Giulia Marianetti, Marco Lessi, Renzo Rossi, MANZINI, CHIARA, LESSI, MARCO, Fabio Bellina, BELLINA, FABIO   +9 more
core   +1 more source

Reaction of diethyl phosphorisocyanatidite with 3,4-dichloro-5-hydroxy-2(5H)-furanone

, 2020
Reaction of diethyl phosphorisocyanatidite with 3,4-dichloro-5-hydroxy-2(H)-furanone (mucochloric acid) is accomplished by mixing the reagents and leads to a bicyclic phosphonamidate.
Loginova I., Galkin V., Volodina Y., Sakhibullina V., Cherkasov R., Polezhaeva N.   +5 more
core  

Furanone derivative and sesquiterpene from Antarctic marine-derived fungus Penicillium sp. S-1-18

Journal of Asian Natural Products Research, 2017
A new furanone derivative, butanolide A (1), and a new sesquiterpene, guignarderemophilane F (2), together with six known compounds, were isolated from the fungus Penicillium sp. S-1-18 derived from Antarctic marine. The new structures were determined by spectroscopic studies such as 1D- and 2D-NMR and MS analyses.
Yue, Zhou, Yun-Hai, Li, Hao-Bing, Yu, Xiao-Yu, Liu, Xiao-Ling, Lu, Bing-Hua, Jiao   +5 more
openaire   +2 more sources

Image_1_Paradigm Shift in Drug Re-purposing From Phenalenone to Phenaleno-Furanone to Combat Multi-Drug Resistant Salmonella enterica Serovar Typhi.TIF

, 2018
Over recent years, typhoid fever has gained increasing attention with several cases reporting treatment failure due to multidrug resistant (MDR) strains of Salmonella enterica serovar Typhi.
Chandrajit Lahiri (5600633), Shama Mujawar (5600627), Derek Gatherer (615779)   +2 more
core   +1 more source