Results 141 to 150 of about 28,655 (201)

A review on the cleavage priming of the spike protein on coronavirus by angiotensin-converting enzyme-2 and furin

, 2020
Anwarul Hasan, Bilal Ahamad Paray, Arif Hussain, Fikry Ali Qadir, Farnoosh Attar, Falah Mohammad Aziz, Majid Sharifi, Hossein Derakhshankhah, Behnam Rasti, Masoumeh Mehrabi, Koorosh Shahpasand, Ali Akbar Saboury, Mojtaba Falahati   +12 more
openalex   +2 more sources

Novel factor VIII variants with a modified furin cleavage site improve the efficacy of gene therapy for hemophilia A [PDF]

, 2016
Giang N. Nguyen, Lindsey A. George, Joshua Siner, Robert J. Davidson, Catherine B. Zander, X. Long Zheng, Valder R. Arruda, Rodney M. Camire, Denise E. Sabatino   +8 more
openalex   +1 more source

CENPU promotes tumorigenesis and stem cell properties in triple‑negative breast cancer by suppressing lysosomal furin degradation. [PDF]

Int J Mol Med
Sun S, Hou Z, Qiang L, Zhou D.
europepmc   +1 more source

Furin inhibition results in absent or decreased invasiveness and tumorigenicity of human cancer cells

, 2001
Daniela Bassi, Ricardo López de Cicco, Haleh Mahloogi, Stanley Zucker, Gary Thomas, Andres J. Klein–Szanto   +5 more
openalex   +1 more source

A novel vector design targeting the blood-brain barrier with the brain-specific AAV-BR1 vector enables abluminal protein secretion from brain endothelial cells in vitro. [PDF]

Fluids Barriers CNS
Laczek B, Thomsen MS, Körbelin J, Burkhart A, Moos T.   +4 more
europepmc   +1 more source

Blood pressure, plasma proteins, and cardiovascular diseases: a network Mendelian randomization and observational study. [PDF]

Eur Heart J
Meena D, Huang J, Smith A, Yarmolinsky J, Wu S, Koskeridis F, Ko YH, Dib MJ, Antonatos C, Vasilopoulos Y, Yu X, Otto GW, Gill D, Mayr M, Elliott P, Dehghan A, Tzoulaki I.   +16 more
europepmc   +1 more source

Rapid virus-free production of recombinant yellow fever virus envelope protein and its in-depth biophysical analysis. [PDF]

Sci Rep
Schelle L, Kuttenlochner W, Sanchez V, Steigenberger B, Finkl K, Schmid M, Douat C, Halldorsson E, Schubert M, Suppmann S.   +9 more
europepmc   +1 more source

The Proinflammatory Secretome of Senescent Cells Can Be Controlled by a HIF2A-Dependent Upregulation and a FURIN-Dependent Cleavage of the ANGPTL4 Secreted Factor. [PDF]

Aging Cell
Makulyte G, Safwan-Zaiter H, Goehrig D, Huna A, Mangelinck A, Mikawa T, Palazzo A, Moudombi L, Medard JJ, Chanal M, Lecot P, Michallet MC, Gavard J, Adnot S, Dubus P, Kondoh H, Mann C, Tan NS, Bertolino P, Flaman JM, Bernard D.   +20 more
europepmc   +1 more source

K5 polysaccharides inhibit SARS-CoV-2 infection by preventing spike-proteolytic priming. [PDF]

Npj Viruses
Milanesi M, Urbinati C, Zimmermann L, Oreste P, Zani A, Caruso A, Caccuri F, Laketa V, Chlanda P, Wade RC, Rusnati M, Paiardi G.   +11 more
europepmc   +1 more source

Structural insights into proprotein convertase activation facilitate the engineering of highly specific furin inhibitors. [PDF]

Nat Commun
Klaushofer R, Bloch K, Eder LS, Marzaro S, Schubert M, Böttcher-Friebertshäuser E, Brandstetter H, Dahms SO.   +7 more
europepmc   +1 more source