Results 51 to 60 of about 1,173 (152)

Recent Perspectives on Anticancer Potential of Coumarin Against Different Human Malignancies: An Updated Review

Food Science &Nutrition, Volume 13, Issue 1, January 2025.
The paper highlights coumarin's ability to induce apoptosis, inhibit cell proliferation, and interfere with cancer cell signaling pathways. Coumarin disrupts key signaling pathways, including NF‐κB and PI3K/Akt, which are crucial for cancer cell survival and proliferation.
Muhammad Shahbaz, Asfa Perween, Ushna Momal, Muhammad Imran, Muhammad Hammad Ul Hassan, Hammad Naeem, Ahmed Mujtaba, Muzzamal Hussain, Suliman A. Alsagaby, Waleed Al Abdulmonem, Mohamed A. Abdelgawad, Ahmed H. El‐Ghorab, Samy Selim, Ehab M. Mostafa, Entessar Al Jbawi   +14 more
wiley   +1 more source

Coumarins from Peucedanum hystrix growing in Mongolia

Mongolian Journal of Chemistry, 2014
It is proved to be that of genus Peucedanum hystrix serve as a source of biologically valuable natural coumarins. Nine angular furocoumarins belonging to class of 2'-substituted and 2',3'-disubstituted 2',3'-dihydrofurocoumarins have been isolated and ...
J Ganbaatar, EE Shults, D Otgonsuren, LD Radnaeva, B Taraskin, D Badamkhand   +5 more
doaj   +1 more source

Herbal Amara extract induces gastric fundus relaxation via inhibition of the M2 muscarinic receptor

Neurogastroenterology &Motility, Volume 37, Issue 1, January 2025.
This preclinical study demonstrates the relaxant effect of Amara herbal extract (containing nine different plant extracts) on fundus smooth muscles dissected from guinea pigs. This relaxant effect occurs via inhibition of M2 muscarinic receptor activity.
Maria‐Riera Piqué‐Borràs, Johann Röhrl, Gerald Künstle   +2 more
wiley   +1 more source

Ficus carica Tree Latex is Used for Treating Warts: Is it a Coincidence or a New Point of View?

Dermatologic Therapy, Volume 2025, Issue 1, 2025.
Background Warts are common skin growths, viral in origin. In fact, many infections arise from members of the human papillomavirus (HPV) family. Traditional treatments for warts have existed to date, but all such procedures can be expensive, invasive, painful, and sometimes ineffective.
Mobina Rahnama, Fatemeh Hajilou, Hadis Nasoori, Naser-Aldin Lashgari, Suraiya Saleem   +4 more
wiley   +1 more source

Atom- and step-economic synthesis of biaryl-substituted furocoumarins, furoquinolones and furopyrimidines by multicomponent reactions and one-pot synthesis

Green Processing and Synthesis, 2013
Atom-efficient multicomponent reactions (MCR) and step-efficient one-pot synthesis are developed for the synthesis of biaryl-substituted furocoumarins, furoquinolones, and furopyrimidines.
Kadam Asha, Bellinger Stephanie, Zhang Wei   +2 more
doaj   +1 more source

Thio and Seleno Derivatives of Angelicin as Efficient Triplet Harvesting Photosensitizers: Implications in Photodynamic Therapy

ChemPhysChem, Volume 25, Issue 24, December 16, 2024.
This work features single atom chalcogen substitution and how faithfully the Angelicin skeleton approaches towards being an efficient PDT photosensitizer upon substituting oxygen with sulfur and selenium. A significant red‐shifted absorption, increased oscillator strength, and spin‐orbit coupling values, along with reduced singlet‐triplet energy gaps ...
Pranay Mohanty, S. Sarang, Saiprakash Rout, Himansu S. Biswal   +3 more
wiley   +1 more source

Cross‐Cohort Gut Microbiome Signatures of Irritable Bowel Syndrome Presentation and Treatment

Advanced Science, Volume 11, Issue 41, November 6, 2024.
Irritable Bowel Syndrome (IBS) is a prevalent disorder of gut‐brain interaction, affecting ≈11% of the global population. This meta‐analysis identified consistent gut microbiome signatures associated with IBS across studies in distinct geographies and cataloged microbiota‐targeted diet patterns for microbiome modulation in IBS.
Junhui Li, Tarini Shankar Ghosh, Elke Arendt, Fergus Shanahan, Paul W. O'Toole   +4 more
wiley   +1 more source

Coumarins from Magydaris pastinacea as inhibitors of the tumour-associated carbonic anhydrases IX and XII: isolation, biological studies and in silico evaluation

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
In an in vitro screening for human carbonic anhydrase (hCA) inhibiting agents from higher plants, the petroleum ether and ethyl acetate extracts of Magydaris pastinacea seeds selectively inhibited hCA IX and hCA XII isoforms.
Benedetta Fois, Simona Distinto, Rita Meleddu, Serenella Deplano, Elias Maccioni, Costantino Floris, Antonella Rosa, Mariella Nieddu, Pierluigi Caboni, Claudia Sissi, Andrea Angeli, Claudiu T. Supuran, Filippo Cottiglia   +12 more
doaj   +1 more source

Modification of Biologically Active Plant Metabolites Via the Transition Metal Catalyzed Reactions

Eurasian Chemico-Technological Journal, 2013
Developed by the author’s research laboratory methods of functionalization of some plant metabolites or their derivatives, viz., the eudesmane-type methylenelactones, diterpene and morphinane alkaloids, furanolabdanoids, and coumarins, using the ...
E. E. Shults
doaj   +1 more source

Preliminary Cytotoxic Study of Some Novel Furo-2-quinolone Compounds

Iraqi Journal of Pharmaceutical Sciences, 2017
In this research, new series of Furo-2-quinolone [FQ] compounds have been synthesized. These novel [FQ] compounds were prepared from coumarin derivatives (Furocoumarins: psoralen and isopsoralen).Identifications of these FQ compounds were performed by ...
Nohad A.AlOmari, Adnan O. Omar, Iklas M. Taher   +2 more
doaj   +3 more sources