Dapagliflozin effect on functional mitral regurgitation and myocardial remodelling: The DEFORM trial
ESC Heart Failure, EarlyView.Abstract Aims Functional mitral regurgitation (FMR) is associated with adverse outcomes in patients with heart failure, and current guideline‐directed medical therapy (GDMT) offers limited efficacy in managing FMR. This study aims to evaluate the therapeutic impact of the sodium‐glucose cotransporter 2 inhibitor (SGLT2i) dapagliflozin in patients with ...
Zhuoshan Huang +18 more
wiley +1 more source
Targeted monitoring for human pharmaceuticals in vulnerable source and final waters [PDF]
, 2012 A range of pharmaceuticals has been detected in soils, surface waters and groundwaters across the world. While the reported concentrations are generally low (i.e. sub μg l-1 in surface waters), the substances have been observed throughout the year across
Bersuder, Phillipe +6 more
core
Contrast-associated acute kidney injury : does it really exist, and if so, what to do about it? [PDF]
, 2019 For decades, when contrast agents are administrated, physicians have been concerned because of the risk of inducing acute kidney injury (AKI). Recent literature questions the existence of AKI induced by contrast, but animal studies clearly showed harmful
Hoste, Eric, Vandenberghe, Wim
core +2 more sources
ESC Heart Failure, EarlyView.Abstract Aims Data support favourable haemodynamic benefits of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) on improving cardiac structural abnormalities and function in patients with heart failure (HF). However, the direct haemodynamic effects of GLP‐1 RAs remain inadequately characterized.
Haoran Jiang +6 more
wiley +1 more source
Effect of nitroprusside on furosemide-induced skeletal teratogenicity in rat fetuses
Iranian South Medical Journal, 2016 Background: Furosemide as a loop diuretic can use in treatment of hypertension, renal or heart failures and cirrhosis, when sodium retention is significant.
Mahmood Khaksary Mahabady +2 more
doaj
Relationship between antihypertensive medications and cognitive impairment: Part II. Review of Physiology and animal studies [PDF]
, 2016 Purpose of Review There is an established association between hypertension and increased risk of poor cognitive performance and dementia including Alzheimer’s disease; however, associations between antihypertensive medications (AHM) and dementia risk are
Carlson, MC +4 more
core +1 more source
Acoustic features are independently associated with heart failure and pulmonary hypertension
ESC Heart Failure, EarlyView.Abstract Introduction Acoustic analysis of speech has discriminated decompensated acute heart failure (HF). Speech rate (SR) and cepstral peak prominence (CPP) variation are among features previously evaluated. However, the association between SR and CPP and chronic stable HF with and without pulmonary hypertension (PH) as well as PH alone have not ...
Jaskanwal Deep S. Sara +6 more
wiley +1 more source
Uji Efektivitas Diuretik Ekstrak Etanol Biji Salak (Salacca Zalacca Varietas Zalacca (Gaert.) Voss) Pada Tikus Putih Jantan Galur Wistar (Rattus Norvegicus) [PDF]
, 2014 This research has purpose to examine the diuretic effects of Salak seed\u27s ethanol extract and to analyze the relationship of dose concentration of Salak seed\u27s ethanol extract upon diuretic effect on Wistar white male mice (Rattus norvegicus).
Latuconsina, N. H. (Novita)
core +3 more sources
European Journal of Heart Failure, EarlyView.Among high‐risk patients with T2D, new oral loop diuretic intensification was frequent and portended adverse prognostic significance. Treatment with canagliflozin significantly reduced the need for loop diuretic intensification. ABSTRACT Aims The sodium–glucose cotransporter 2 inhibitor canagliflozin reduces the risk of heart failure (HF ...
Safia Chatur +11 more
wiley +1 more source
An inhibitory effect of furosemide on sodium reabsorption by the proximal tubule of the rat nephron [PDF]
, 1969 Barry M. Brenner +3 more
openalex +1 more source