Results 241 to 250 of about 42,923 (283)
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Furosemide, Hypertension, and Osteoporosis
JAMA: The Journal of the American Medical Association, 1979To the Editor.— The recent study by Araoye et al further confirms the superiority of hydrochlorothiazide over furosemide for treatment of hypertension in patients with satisfactory renal function (240:1863, 1978). Another point to be made in favor of thiazides over the loop diuretics relates to the effect of long-term treatment on urinary calcium ...
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Furosemide induced hepatotoxicity
The Journal of Pathology, 1981AbstractFurosemide‐induced (400mg/kg ip) hepatotoxicity progressing to centrilobular necrosis was studied by light and electron microscopy in Swiss white mice. Centrilobular glycogen depletion and cytoplasmic foaminess, usually accompanied by extensive vacuolation, were detectable by light microscopy 1 1/2 hr after furosemide.
T. F. McElligott, R. M. Walker
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Effects of furosemide in the newborn
Clinical Pharmacology & Therapeutics, 1978The effects of furosemide on electrolyte and water excretion were determined in 9 neonates with fluid overload states. Hourly measurements of urine volume, serum and urine Na+, K+, Cl−, creatinine, and blood urea nitrogen were done before and after the intravenous or intramuscular injection offurosemide (1 mg/kg).
Claire Dupont +3 more
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Ototoxicity Induced by Furosemide
New England Journal of Medicine, 1970FUROSEMIDE is a diuretic that has achieved wide use because of its great potency as a saluretic agent and its low order of toxicity.
Gabriel H. Schwartz +4 more
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Furosemide disposition in cirrhosis
Clinical Pharmacology and Therapeutics, 1982Furosemide disposition after rapid intravenous injection (80 mg) was studied in 10 normal healthy subjects and eight patients with cirrhosis and ascites. In the cirrhotic patients the elimination half-life was modestly longer (81.0 +/- 8.0 min and 60.2 +/- 5.8 min). This prolongation was not associated with a difference in systemic clearance (156 +/- 7
Robert A. Branch +4 more
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Furosemide-Induced Ototoxicity
Annals of Internal Medicine, 1979Excerpt The Adverse Drug Reaction Reporting Program of the Division of Drug Experience, Food and Drug Administration (1), has received 29 case reports of deafness associated with the administration...
Kevin L. Gallagher, Judith K. Jones
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On the fate of furosemide in man
European Journal of Clinical Pharmacology, 197535S-furosemide was administered orally (n=7) or i.v. (n=2) to healthy subjects. The average gastrointestinal uptake estimated by comparison of the urinary recovery of label and the areas under the plasma curves after the two routes of administration was 65%.
Björn Lindström +3 more
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Placental transfer of furosemide
Clinical Pharmacology & Therapeutics, 1978After oral administration of furosemide to 18 pregnant women on the day of delivery, substantial concentrations of the drug were detected in umbilical cord vein plasma as well as in amniotic fluid. The ratio between the furosemide concentrations in maternal vein plasma and in umbilical cord plasma increased with time and approximated unity at 8 to 10 ...
Margaretha Groschinsky-Grind +3 more
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Pharmacokinetics of furosemide in neonates
European Journal of Clinical Pharmacology, 1982The pharmacokinetics of furosemide was evaluated in 12 newborns who received the drug transplacentally, and in 21 neonates who received it directly for therapeutic reasons. In the first group, the apparent plasma half-lives ranged from 96 to 6.8 h with a significant inverse relationship (p less than 0.01) between the gestational age and the elimination
M Broquaire +3 more
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Tobramycin-Furosemide Interaction
Drug Intelligence & Clinical Pharmacy, 1984A 70-year-old, 75-kg white female with a history of congestive heart failure was admitted with a two-week episode of progressive shortness of breath, increased abdominal distension, and ankle edema. Sputum Gram stains revealed gram-negative bacilli, and the patient was started on a loading dose of tobramycin 150 mg (2 mg/kg) over 30 minutes.
Christopher Lyman +2 more
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