Results 31 to 40 of about 19,523 (262)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

MODELO DE ONDAS CINEMÁTICAS NA SOLUÇÃO DO PROBLEMA INVERSO DA IRRIGAÇÃO POR SULCO EM TEMPO REAL

Revista Brasileira de Engenharia Agrícola e Ambiental
RESUMO Um modelo matemático computacional de ondas cinemáticas foi desenvolvido para interagir num processo de otimização não-linear na solução do problema inverso da irrigação por sulco, que consiste na determinação das características de infiltração d ...
Carlos Alberto Vieira de Azevedo, Wynn R. Walker, Gary P. Merkley   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Economic Return for Maize Crop under Surface Irrigation System [PDF]

Journal of Soil Sciences and Agricultural Engineering
The field experiment was conducted at Sidi Salem city, KafrElshekh governorate, Egypt. Located at latitude 310 27'N, longitude 300 78'E and 6,1m Altitude during season 2023 to determine the performance of alternate furrow irrigation and effect of water ...
Narmeen Morsy, A. Awwad, M. Aiad
doaj   +1 more source

STATUS OF N, P AND K IN SOIL AND PLANT AS AFFECTED BY SOIL MOISTURE AND IRRIGATION SYSTEMS [PDF]

Journal of Soil Sciences and Agricultural Engineering, 2003
A field experiment was carried out to study the effect of irrigation pI nt to attain sou moisture status of 75, 100 and 125 % available water (AVV) under two irrigation systems: drip and furrow on status of macro nutrients in soil and maize (Zea mays ...
A. EI-Mneasy, A. EI-Gazzar,
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

The maternal-effect gene cellular island encodes aurora B kinase and is essential for furrow formation in the early zebrafish embryo.

PLoS Genetics, 2009
Females homozygous for a mutation in cellular island (cei) produce embryos with defects in cytokinesis during early development. Analysis of the cytoskeletal events associated with furrow formation reveal that these defects include a general delay in ...
Taijiro Yabe, Xiaoyan Ge, Robin Lindeman, Sreelaja Nair, Greg Runke, Mary C Mullins, Francisco Pelegri   +6 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Cleavage furrow positioning [PDF]

The Journal of Cell Biology, 2004
To complete the cell cycle, the cleavage furrow draws the plasma membrane toward the cell center, pinching the cytoplasm into two lobes that are subsequently separated into two cells. The position of the cleavage furrow is induced by the mitotic spindle during early anaphase.
openaire   +2 more sources